1 to 10 of 125 trials

• A Study to Assess the Safety and Pharmacokinetics of an Inhibitor of Poly ADP-Ribose Polymerase-1 (PARP)

  conditions:	Ovarian Neoplasms ; BRCA1 Protein ; BRCA2 Protein
  interventions:	KU-0059436 (AZD2281)(PARP inhibitor)
  last updated:	2009 Sep 22
  status:	active, not recruiting
  sponsor:	AstraZeneca

   

• Genetic Counseling in Women at Risk for BRCA1 or BRCA2 Mutations

  conditions:	Breast Cancer
  interventions:	counseling intervention
  last updated:	2009 Mar 7
  status:	active, not recruiting
  sponsor:	Lombardi Cancer Research Center

   

• Outcomes of Education and Counseling for BRCA1 Testing

  conditions:	Breast Neoplasms ; Ovarian Neoplasms
  interventions:	none
  last updated:	2008 Mar 3
  status:	completed
  sponsor:	National Human Genome Research Institute (NHGRI)

   

• Impact of Testing Positive for the BRCA1 or BRCA2 Mutation in Young Women Who Are BRCA1 or BRCA2 Mutation Carriers

  conditions:	brca1 Mutation Carrier ; brca2 Mutation Carrier ; Sexuality and Reproductive Issues
  interventions:	telephone-based intervention ; questionnaire administration ; psychosocial assessment and care
  last updated:	2009 Aug 6
  status:	recruiting
  sponsor:	National Cancer Institute (NCI)

   

• Studying Breast Cancer Risk in Women Who Are BRCA1/BRCA2 Mutation Carriers

  conditions:	brca1 Mutation Carrier ; brca2 Mutation Carrier ; Breast Cancer
  interventions:	DNA analysis ; mutation analysis ; polymorphism analysis ; laboratory biomarker analysis ; evaluation of cancer risk factors
  last updated:	2009 May 9
  status:	recruiting
  sponsor:	Gynecologic Oncology Group

   

• Breast Cancer Risk in Women Who Are BRCA1/BRCA2 Mutation Carriers

  conditions:	brca1 Mutation Carrier ; brca2 Mutation Carrier ; Breast Cancer
  interventions:	DNA analysis ; mutation analysis ; polymorphism analysis ; laboratory biomarker analysis ; evaluation of cancer risk factors
  last updated:	2009 Jul 15
  status:	active, not recruiting
  sponsor:	Gynecologic Oncology Group

   

• BRCA1 Haploinsufficiency and Gene Expression

  conditions:	BRCA1 Mutations
  interventions:	none
  last updated:	2009 May 5
  status:	recruiting
  sponsor:	Memorial Sloan-Kettering Cancer Center

   

• Establishing the Incidences of BRCA1 and BRCA2 Mutation by Combining DHPLC and Direct Sequencing in Ovarian Cancer

  conditions:	Ovarian Cancer
  interventions:	none
  last updated:	2005 Sep 9
  status:	recruiting
  sponsor:	National Taiwan University Hospital

   

• Telephone-Based Genetic Counseling or Standard Genetic Counseling in Women at Risk of Carrying the BRCA1 or BRCA2 Mutation

  conditions:	Breast Cancer
  interventions:	mutation analysis ; counseling intervention
  last updated:	2009 Jul 15
  status:	recruiting
  sponsor:	Lombardi Cancer Research Center

   

• National Screening in Denmark With MR Versus Mammography and Ultrasound of Women With BRCA1 or BRCA2 Mutations

  conditions:	Breast Cancer
  interventions:	MR mammography ; MR
  last updated:	2009 Jan 27
  status:	recruiting
  sponsor:	Danish Breast Cancer Cooperative Group