Rat model with naturally occuring and oxidative stress induced liver tumorigenesis

score: 100 | Rattus norvegicus |   RNA Expression

The Long-Evans Cinnamon rat is a model with naturally occurring and oxidative stress-induced hepatotumorigenesis. Gene expression patterns were analyzed by profiling liver tissue from naïve status (4wk) rats through to those with chronic hepatitis (26 and 39wk) to tumor development (67wk).

Source: NextBio Library/Oncology

Gene expression in mouse liver in response to fasting and sugar-fed conditions

score: 99 | Mus musculus |   RNA Expression

We have monitored global changes in gene expression in mouse liver in response to fasting and sugar-fed (50% (w/v) sugar solution composed of 40% glucose 10% sucrose) conditions using 8-15 week old 129/sv males.

Authors: Bauer Matthias, Hamm C Anne, Bonaus Melanie et al.

Organization: Forschungszentrum Karlsruhe Institute of…