telomere - NextBio

Search Term: telomere

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Individual Studies
Wild type yeast, mre11delta, rad50delta, and spo11Y135F at meiosis Saccharomyces cerevisiae Mre11, together with Rad50 and Xrs2/NBS, plays pivotal roles in homologous recombination, repair of DNA double strand breaks (DSBs), activation of damage-induced checkpoint, and telomere maintenance. Using DNA microarray assays to analyze yeast mutants (mre11delta, rad50delta, and spo11Y135F) defect… Authors: Kugou Kazuto, Sasanuma Hiroyuki, Matsumoto Kouji, Shirahige Katsuhiko, Ohta Kunihiro Organization: RIKEN Shibata Distinguished Scientist La… Total # Biosets: 2	The PI3K domain of Tra1 is required for transcriptional regulation Saccharomyces cerevisiae Tra1 is an essential component of the S. cerevisiae SAGA and NuA4 complexes. Using targeted mutagenesis, we identified residues within its C-terminal phosphatidylinositol-3 kinase (PI3K) domain that are required for function. The phenotype of tra1-P3408A, S3463A and SRR3413-3415AAA included temperat… Authors: Mutiu AI, Hoke SM, Genereaux J, MacKenzie K, Hannam C, Abrassart D et al. Organization: University of Western Ontario Biochemist… Total # Biosets: 3

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Telomere Repair Gene Mutation in Inflammatory Bowel Disease

conditions: Inflammatory Bowel Disease ; IBD

interventions: none
Nutrition and Lifestyle Changes in Patients With Previously Untreated Stage I or Stage II Prostate Cancer

conditions: Prostate Cancer

interventions: exercise intervention ; gene expression analysis ; polymerase chain reaction ; proteomic profiling ; reverse transcriptase-polymerase chain reaction ; laboratory biomarker analysis ; medical chart review ; questionnaire administration ; psychosocial assessment and care ; quality-of-life assessment ; support group therapy ; therapeutic dietary intervention

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