Functional and Genomic Profiling of Effector CD8 T Cell Subsets

Mus musculus

Using killer cell lectin-like receptor G1 as a marker to distinguish terminal effector cells from memory precursors, we found that despite their diverse cell fates both subsets possessed remarkably similar gene expression profiles and functioned as equally potent killer cells. However, only the memo…

Organization: Emory University Emory University School…

Total # Biosets: 6

OT-I T cells undergoing Lymphopenic Homeostatic Proliferation induced by Irradiation

Mus musculus

A time course of OTI CD8 T cells transferred to irradiated syngeneic hosts (or unirradiated hosts as control)

Authors: Goldrath W Ananda, Luckey C. John, Park Richard, Benoist Christophe, Mathis Diane

Organization: Joslin Diabetes Center Immunology and Im…

Total # Biosets: 5