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Maladaptive pattern of drug or alcohol use that may lead to social, occupational, psychological, or physical problems.

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Data Correlations | 6 studies

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Genes category icon Genes
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GABRA2 100 100
SLC29A1 100 100
FAAH 100 100
SLC6A3 100 100
HTR2A 100 100
GABBR2 100 100
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Biogroups category icon Biogroups
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Protein kinase, C-terminal 100 100
Monoamine GPCRs 100 100
Neuroactive Ligand Receptor Interac… 98 98
Nucleotide GPCRs 95 95
Phox-like 93 93
Pentose and Glucuronate Interconver… 93 93
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Individual Studies

  • Brain expression in alcohol preferring rat strain

    Rattus norvegicus Rattus norvegicus | RNA Expression   RNA Expression

    The objective of this study was to test the hypothesis that innate differences in gene expression in the brain could

    Authors: Strother WN, Kimpel MW, McClintick JN et al.

    Organization: Indiana University Psychiatry W.J. McBri…

  • Morphine effects on striatal transcriptome in four inbred mouse strains

    Mus musculus Mus musculus | RNA Expression   RNA Expression

    Chronic opiate use produces molecular and cellular adaptations in the nervous system, leading to tolerance, physical dependence and addiction. Genome-wide comparison of morphine-induced changes in brain transcription of mouse strains with different opioid-related phenotypes provides an opportunity t…

    Authors: Korostynski M, Piechota M, Przewlocki R

    Organization: Institute of Pharmacology PAS Molecular …
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Associated Researchers

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Thought leaders and organizations working on research involving substance abuse.

View All Author iconAuthors
  • StĂ©phane Potvin
  • Emmanuel Stip
  • Michele Staton-Tindall
  • Faye Taxman
  • Frank M Orson
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • National Institute on Drug Abuse (NIDA)
  • Department of Veterans Affairs
  • Oregon Research Institute
  • Yale University
  • VU University of Amsterdam
View All Affiliations icon Organizations
  • University of California
  • Columbia University College of Physicians and Surgeons
  • University of Montreal
  • National Institute on Drug Abuse
  • University of Kentucky

Clinical Trials | 4,575 trials

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News | 28 stories

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Community

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