Systemic inflammatory response syndrome with a proven or suspected infectious etiology. When sepsis is associated with organ dysfunction distant from the site of infection, it is called severe sepsis. When sepsis is accompanied by HYPOTENSION despite adequate fluid infusion, it is called SEPTIC SHOCK.

Data Correlations | 63 studies

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Genes	Score
CASP12	100
MMP8	100
IL1R2	94
ANXA3	94
MMP9	92
DEFA4	91

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Biogroups	Score
I43 - oprin	100
All Peptidase Inhibitors	98
Hematopoietic Cell Lineage	98
Nucleotide-binding, alpha-beta plai…	98
Erythropoietin Mediated Neuroprotec…	98
IL-1R Pathway	98

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Individual Studies

Comparison of SVG-A glial cells and SVGR2 glial cells Homo sapiens |   RNA Expression SVGR2 cells are glial cells which are derived from SVG-A cells. They were created by subjecting SVG-A cells to multiple rounds of lytic infection by the human polyomavirus JCV. SVGR2 cells are the cells that survived this process and are resistant to JCV infection. This experiment was designed to id… Authors: Atwood J Walter, Manley Kate Organization: Brown University 70 Ship St. Providence …

Antiviral therapies peginterferon against hepatitis C Homo sapiens |   RNA Expression Time series of gene expression arrays before and during treatment of Hepatitis C; days 0, 1, 2, 7, 14 and 28 for 69 participants (IDs 1 through 69 are used). Authors: Taylor W Milton, Tsukahara Takuma, Brodsky Leonid et al. Organization: Indiana University Biology 343 Jordan Ha…

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Literature | 89,466 results

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• Counteracting clotting in sepsis.

  Authors: Mark L Kahn

  Nature medicine 2008 Sep

• Functional roles for C5a receptors in sepsis.

  Authors: Daniel Rittirsch, Michael A Flierl, Brian A Nadeau, Danielle E Day, Markus Huber-Lang, Charles R Mackay, Firas S Zetoune, Norma P Gerard, Katherine Cianflone, Jörg Köhl,…

  Nature medicine 2008 May

Associated Researchers

Thought leaders and organizations working on research involving sepsis.

View All Authors

• Peter A Ward
• Arturo Zychlinsky
• Luis Ulloa
• Tom van der Poll
• Mauro Perretti

View All Clinical Trials Sponsors

• Eli Lilly and Company
• Eunice Kennedy Shriver National Institute of Child Health and Human De…
• University Hospital, Basel, Switzerland
• Takeda Global Research & Development Center, Inc.
• Mayo Clinic

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• University of Michigan Medical School
• Vanderbilt University School of Medicine
• University of Pennsylvania
• Oklahoma Medical Research Foundation
• Brigham and Women's Hospital and Harvard Medical School

Clinical Trials | 1,901 trials

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• Neutropenic Fever, Inflammatory Markers and Sepsis in Haematological Patients

  conditions: Sepsis

  interventions: Severe sepsis vs. non-severe sepsis

   

• Septic Encephalopathy and Late Cognitive Dysfunction

  conditions: Sepsis ; Severe Sepsis

  interventions: n-3 fatty acids

   

News | 155 stories

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• Health Matters : What is Sepsis ?

  PR-inside.com. - November 20, 2009

• Hospital-Acquired Sepsis, Pneumonia a 'Growing Menace' news

  e-Healthcare.

Community

View All NextBio Users | 7 people

• Nicole  Smits

  Research Associate

  Dartmouth Medical School

• Gilles François  Ndayisaba

NextBio Groups

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