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pre-B cell allelic exclusion
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NextBio Summary
General Info
Body Atlas
Most Correlated Tissues
Thymus gland
Lymph nodes
Tonsil
Spleen
Duodenum
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Disease Atlas
Most Correlated Diseases
Lymphocytopenia
Disease due to Orthopoxvirus
Ataxia-telangiectasia syndrome
Severe combined immunodeficiency disease
Cancer of thymus
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Pharmaco Atlas
Most Correlated Compounds
fragment C, human serum albumin
Phytohemagglutinins
N-oleoylethanolamine
8-((4-chlorophenyl)thio)cyclic-3',5'-AMP
Lindane
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Knockdown Atlas
Most Correlated Gene Perturbations
CPSF2
SBDS
DDAH1
FANCG
BACH2
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Curated Studies
Most Correlated Studies
The Immunological Genome Project - Immune cell lineage differentiation and maturation
OMIM - Malignant neoplasms
T cell acute lymphoblastic leukemia Jurkat cells treated with TNF, PMA and ionomycin
Jurkat T cells activated with PMA and PHA for different time points
T-ALL T6E cells with Notch transcription complexes treated with a gamma secretase inhibitor
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Literature
Most Relevant Literature
An important role of phospholipase Cgamma1 in pre-B-cell development and allelic exclusion.
Variegated transcriptional activation of the immunoglobulin kappa locus in pre-b cells contributes t…
Unexpected requirement for ZAP-70 in pre-B cell development and allelic exclusion.
VPREB3: cDNA characterization and expression in human and chromosome mapping in human and mouse.
The cytoplasmic domains of immunoglobulin (Ig) alpha and Ig beta can independently induce the precur…
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Clinical Trials
Most Relevant Clinical Trials
Polymorphism and Auto-reactive B and T Cells Subsets in Adult's Immune Thrombocytopenia (ITP)
Sirolimus, Cyclosporine, and Mycophenolate Mofetil in Preventing Graft-versus-Host Disease in Treati…
Abatacept Reduced Intensity for Non-Malignant Diseases
Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a D…
Therapeutic Effects Of Epstein-Barr Virus Immune T-Lymphocytes Derived From A Normal HLA- Compatible…
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