A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters across the synaptic cleft and transmit the signal to the postsynaptic membrane.

Data Correlations | 978 studies

View All

Normal tissues	Score
Substantia nigra	100
Dorsal striatum	95
Putamen	89
Preoptic area	88
Large intestine	86
Nucleus accumbens	84

View Top Normal tissues

Compounds	Score
Miconazole	100
Nimesulide	98
Atorvastatin	98
Diethylstilbestrol	94
Valproic Acid	94
Chlorambucil	93

View Top Compounds

Diseases	Score
Eaton Lambert myasth…	100
Multiple pterygium s…	96
Tympanic membrane pe…	93
General adaptation s…	87
Huntington's disease	86
Benign neoplasm of f…	86

View Top Diseases

Individual Studies

Liver Pharmacology and Xenobiotic Response Repertoire score: 100 | Rattus norvegicus |   RNA Expression A definition of RNA expression changes that correlate with liver response programs and an understanding of the similarities and differences in responses to different classes of chemicals would aid in new chemical or drug characterization and add to our understanding of liver biology. Authors: Natsoulis G, Pearson CI, Gollub J et al. Organization: Iconix Biosciences 325 E. Middlefield Rd…

Non-genotoxic Hepatocarcinogens (Iconix study) score: 88 | Rattus norvegicus |   RNA Expression We have developed a short-term in vivo rat assay that predicts whether non-genotoxic chemicals are likely to induce hepatic tumors based on transcript profiles in the liver. Using a large independent test set, assay accuracy was found to be superior to existing pathological and genomic markers. Comp… Authors: Fielden MR, Brennan R, Gollub J Organization: Iconix Biosciences 325 E. Middlefield Rd…

View All Individual Studies

Literature | 11,856 results

View All

• PIP3 controls synaptic function by maintaining AMPA receptor clustering at the postsynaptic membrane.

  Authors: Kristin L Arendt, María Royo, Mónica Fernández-Monreal, Shira Knafo, Cortney N Petrok, Jeffrey R Martens, José A Esteban

  Nature neuroscience 2010 Jan

• Syndapin promotes formation of a postsynaptic membrane system in Drosophila.

  Authors: Vimlesh Kumar, Robert Fricke, Debjani Bhar, Suneel Reddy-Alla, K S Krishnan, Sven Bogdan, Mani Ramaswami

  Molecular biology of the cell 2009 Apr

Associated Researchers

Thought leaders and organizations working on research involving postsynaptic membrane.

View All Authors

• Michael D Ehlers
• Daniel Choquet
• Antoine Triller
• Joshua R Sanes
• J Kirsch

View All Clinical Trials Sponsors

• NeuroBioPharm Inc.
• Summa Health System

View All Organizations

• Duke University Medical Center
• University of California
• Picower Institute for Learning and Memory
• University of Ottawa
• University of Michigan Medical School

Clinical Trials | 2 trials

View All

• A Pilot Study to Investigate Fenoldopam Usage in the Prevention of Postoperative Renal Dysfunction in Patients at a High Risk for Renal Impairment During Cariopulmonary Bypass for Cardiac Surgery

  conditions: Cardiac Surgery With Cardiopulmonary Bypass

  interventions: Fenoldopam

   

• Neptune Krill Oil (NKO™) in Early Stage Alzheimer's Disease (MNEMOSYNE)

  conditions: Early Onset Alzheimer Disease

  interventions: Neptune Krill Oil ; Fish Oil ; Placebo (soy oil)

   

Community

View All NextBio Users | 1 person

• Luisa  Mota-Vieira

  Principal Investigator

  Hospital of Divino Espirito Santo of Ponta Delgada, EPE

NextBio Groups

• No NextBio groups were found for “postsynaptic membrane”.
  Be the first to start a group and share your interests with others within the NextBio community.

search → result

search → result