Cooperative Signaling in the STAT3 and NF-kB Pathways in Subtypes of diffuse large B cell lymphoma

Homo sapiens

Here we show that the NF-kB pathway induces the expression of the cytokines IL-6 and IL-10 in activated B cell-like DLBCL cell lines, which also have high levels of total and phosphorylated STAT3 protein, suggesting autocrine signaling.

Organization: National Cancer Institute Metabolism Bra…

Total # Biosets: 14

A predictive heart failure expression profile in Ren2 rat left ventricles

Rattus norvegicus

The intercalated disc of cardiac myocytes is emerging as a crucial structure in the heart. Loss of intercalated disc proteins like N-cadherin causes lethal cardiac abnormalities, mutations in intercalated disc proteins cause human cardiomyopathy. A comprehensive screen for novel mechanisms in failin…

Authors: van Erk Arie, Schroen Blanche, Pinto Yigal

Organization: University Maastricht BiGCaT Bioinformat…

Total # Biosets: 2