A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization.

Data Correlations | 1,150 studies

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Normal tissues	Score
Penis	100
Esophagus	93
Pylorus	91
Mucosa of mouth	89
Fundus of stomach	82
Subdivision of subst…	82

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Compounds	Score
Staphylococcal Enter…	100
C00377	93
Marshall's Reagent	90
Protein	88
Epo	87
Concanavaline A	87

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Diseases	Score
Acute biphenotypic l…	100
Ebola hemorrhagic fe…	95
Infection by Aspergi…	95
Systemic inflammator…	91
Refractory anemia wi…	89
Acute HIV infection	86

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Individual Studies

PPARg regulated gene expression in human dendritic cells score: 100 | Homo sapiens |   RNA Expression In order to gain insights into how PPARg regulates different facets of dendritic cell (DC) differentiation, we sought to identify PPARg regulated genes and gene networks in monocyte-derived dendritic cells using global gene expression profiling. We employed an exogenous ligand activation approach us… Authors: Szatmari I, Nagy T, Agostini M et al. Organization: University of Debrecen Department of Bio…

Innate immune responses to TREM-1 activation score: 89 | Homo sapiens |   RNA Expression TREM-1 (triggering receptor expressed on myeloid cells-1) is an orphan immunoreceptor expressed on monocytes, macrophages, and neutrophils. TREM-1 associates with and signals via the adapter protein DAP12/TYROBP, which contains an ITAM. TREM-1 activation by receptor cross-linking has been shown to b… Authors: Jelinsky A Scott, Dower Ken Organization: Wyeth Research Biological Technologies B…

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Literature | 13,244 results

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• Regulation of MBK-2/DYRK by CDK-1 and the pseudophosphatases EGG-4 and EGG-5 during the oocyte-to-embryo transition.

  Authors: Ken Chih-Chien Cheng, Richard Klancer, Andrew Singson, Geraldine Seydoux

  Cell 2009 Oct 30

• Antiapoptotic role for ornithine decarboxylase during oocyte maturation.

  Authors: Yong Zhou, Chunqi Ma, Jennifer Karmouch, Hadia Arabi Katbi, X Johné Liu

  Molecular and cellular biology 2009 Apr

Associated Researchers

Thought leaders and organizations working on research involving oocyte maturation.

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• Khaled Machaca
• Shirley Haun
• Richard M Schultz
• Claude Prigent
• Sagit Sela-Abramovich

View All Clinical Trials Sponsors

• Organon
• Universitair Ziekenhuis Brussel
• Eugonia
• Assaf-Harofeh Medical Center
• Hadassah Medical Organization

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• University of Arkansas for Medical Sciences
• University of Texas Southwestern Medical Center
• Weizmann Institute of Science
• Center for Cell Dynamics
• Ottawa Health Research Institute

Clinical Trials | 31 trials

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• Differential Regulation of VEGF, Cadherin, Angiopietin 2 by Trigger Oocyte Maturation With GnRHa vs hCG in Donors

  conditions: Messurement Levels of VEGF

  interventions: none

   

• Concomitant Administration of FSH With HCG Improves Oocyte Maturation and Quality Double -Blinded Randomized Trial

  conditions: Infertility

  interventions: Bravelle(follicle stimulating hormone) ; Saline ( placebo)

   

News | 2 stories

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• What Is Ovulation? What Is The Ovulation Calendar?

  Medical News Today. - May 21, 2009

• ERK1 And ERK2 Activities Are Key To Ovarian Functions And Fertility

  Medical News Today. - May 15, 2009

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