A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)

Literature | 8,311 results

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• Effects of oropharyngeal exercises on patients with moderate obstructive sleep apnea syndrome.

  Authors: Kátia C Guimarães, Luciano F Drager, Pedro R Genta, Bianca F Marcondes, Geraldo Lorenzi-Filho

  American journal of respiratory and critical care medicine 2009 May 15

• Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome.

  Authors: Silke Ryan, Cormac T Taylor, Walter T McNicholas

  Circulation 2005 Oct 25

Associated Researchers

Thought leaders and organizations working on research involving obstructive sleep apnea syndrome.

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• Walter T McNicholas
• Silke Ryan
• Danielle Friberg
• Jingtao Huang
• Leila Kheirandish-Gozal

View All Clinical Trials Sponsors

• University Hospital, Grenoble
• University of Zurich
• University of Chicago
• Irmandade da Santa Casa de Misericoridia de Limeira
• University of Rochester

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• St Vincent's University Hospital
• Children's Hospital of Philadelphia
• Chiba University
• University of São Paulo Medical School
• Université Bordeaux 2

Clinical Trials | 273 trials

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• CEP-10953 in Treatment of Excessive Sleepiness Associated With Obstructive Sleep Apnea/Hypopnea (OSA/H) Syndrome

  conditions: Sleep Apnea, Obstructive ; Sleep Apnea Syndromes

  interventions: CEP-10953

   

• Cytokine Profiles in Children With Obstructive Sleep Apnea

  conditions: Obstructive Sleep Apnea Syndrome

  interventions: tonsillectomy

   

Community

View All NextBio Users | 1 person

• Leila   Kheirandish Gozal

  Associate Professor of Pediatrics

  University of Chicago

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