Time course of bone marrow derived cells from mice stimulated with RANKL to generate osteoclasts

Mus musculus

The receptor activator of NF-B ligand (TNFSF11/RANKL) produced by osteoblasts and activated immune cells initiates the development of osteoclasts in the bone marrow. Using time course expression data, the intrinsic processes and the extrinsic factors that control osteoclastogenesis were identified.

Source: NextBio Library/Stem Cells, Differentiation & Development

Total # Biosets: 6

Primary mouse megakaryocyte differentiation

Mus musculus

Megakaryocyte (MK) differentiation is well described in morphologic terms but its molecular counterparts and the basis for platelet release are incompletely understood. We profiled mRNA expression in populations of primary mouse MKs representing successive differentiation stages. Genes associated wi…

Authors: Shivdasani RA, Chen Z, Hu M

Organization: Dana-Farber Cancer Institute Medical Onc…

Total # Biosets: 3