general term for a group of inherited disorders which are characterized by progressive degeneration of skeletal muscles.

Data Correlations | 19 studies

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Genes	Score
DMD	100
LMNA	100
LAMA2	100
COL6A1	100
COL6A3	100
DMPK	100

View Top Genes

Biogroups	Score
Striated Muscle Contraction	100
ECM Receptor Interaction	100
Cell Communication	99
Collagen helix repeat	98
Focal Adhesion	98
Collagen triple helix repeat	98

View Top Biogroups

Individual Studies

mdx mutant mouse sketetal muscle Mus musculus |   RNA Expression Leg muscle of mdx mutants and controls on days 7,14, and 23. Authors: Porter JD Organization: Case Western Reserve University Neurolog…

Enhancing integrin alpha7 expression effects on mouse myoblasts Mus musculus |   RNA Expression Analysis of C2C12 myoblast induced with tetracycline to enhance integrin alpha7 expression. Integrin alpha7 is the major laminin binding integrin in muscle cells. Enhancing its expression has been demonstrated to alleviate pathology in a murine model of Duchenne muscular dystrophy. Results of this s… Authors: Liu Jianming, Kaufman J Stephen Organization: University of Illinois at urbana-champai…

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Literature | 564 results

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• Muscling in: Gene therapies for muscular dystrophy target RNA.

  Authors: Joel R Chamberlain, Jeffrey S Chamberlain

  Nature medicine 2010 Feb

• Interventions for muscular dystrophy: molecular medicines entering the clinic.

  Authors: Kate Bushby, Hanns Lochmüller, Stephen Lynn, Volker Straub

  Lancet 2009 Nov 28

Associated Researchers

Thought leaders and organizations working on research involving muscular dystrophy.

View All Authors

• Francesco Muntoni
• Hanns Lochmüller
• Paula R Clemens
• Volker Straub
• Craig McDonald

View All Clinical Trials Sponsors

• Cooperative International Neuromuscular Research Group
• PTC Therapeutics
• National Center for Research Resources (NCRR)
• National Institute of Arthritis and Musculoskeletal and Skin Diseases …
• Assistance Publique - Hôpitaux de Paris

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• Newcastle University
• University of California
• Radboud University Nijmegen Medical Centre
• University of Washington
• San Raffaele Biomedical Park Foundation of Rome

Clinical Trials | 109 trials

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• Myotonic Dystrophy and Facioscapulohumeral Muscular Dystrophy Registry

  conditions: Myotonic Dystrophy ; Muscular Dystrophy, Facioscapulohumeral ; Muscular Dystrophy

  interventions: none

   

• Gentamicin Treatment of Muscular Dystrophy

  conditions: Becker Muscular Dystrophy ; Duchenne Muscular Dystrophy

  interventions: Gentamicin

   

News | 60 stories

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• Chemical that may protect hearts of muscular dystrophy patients discovered

  Science Daily. - March 14, 2010

• Researchers discover chemical that may protect hearts of muscular dystrophy patients

  Eurekalert Medicine_health. - March 14, 2010

Community

View All NextBio Users | 3 people

• Filippo  Buccella

  President

  Parent Project onlus

• Peter  Ianakiev

  Scientist

  University of Connecticut Health Ctr

View All NextBio Groups | 1 group

• Duchenne muscular dystrophy research

  4 members

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