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Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
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| Vestibular nuclear c… |
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| Inferior ganglion of… |
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| Subthalamic nucleus |
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| Midbrain |
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| Substantia nigra |
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| Trigeminal ganglion |
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| Paeonol |
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| Oxypaeoniflora |
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| Peoniflorin |
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| Neurokinin B |
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| Matrigel |
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| Dasatinib |
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Authors: Andrew P Jackson
Nature genetics 2009 JunAuthors: Antonina Roll-Mecak, Francis J McNally
Current opinion in cell biology 2010 FebThought leaders and organizations working on research involving microtubule.
conditions: Advanced Cancer
interventions: EPC2407 (crinobulin)
conditions: Hematological Malignancies
interventions: ABT-751
PhD
IRB
Lecturer
Palacky University
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