Human mammary cell subpopulations FACS sorted based on expression of CD49f and EpCAM

Homo sapiens

To delineate epithelial subpopulations in human mammary tissue, hematopoietic and endothelial cells were depleted from freshly isolated cell suspensions derived from reduction mammoplasties. The resultant Lin- population was fractionated into four distinct subpopulations using CD49f (α6-integrin) an…

Source: NextBio Library/Atlas - Organs, tissues and cell types

Total # Biosets: 6

Mouse mammary tumor-initiating cells

Mus musculus

Using a syngeneic p53 null mouse mammary gland tumor model that closely mimics human breast cancer, we have identified by limiting dilution transplantation as well as in vitro mammosphere and clonogenic assays a Lin-CD29HighCD24High subpopulation of tumor-initiating cells.

Authors: Zhang Mei

Organization: Baylor College of Medicine One Baylor Pl…

Total # Biosets: 16