NextBio

Help

mechanistic target of rapamycin (serine/threonine kinase)

binds the complex formed by the immunosuppressive drug rapamycin and its receptor FKBP12; may play a role in the cell cycle G1 to S transition [RGD]

View Gene Details



Data Correlations | 1,362 studies

Help for Data Correlations View All
Tissues category icon Normal tissues
Score Help
Zygote 100 100
Vomeronasal organ 98 98
Set of raphe nuclei 96 96
Femur 96 96
Spinal cord 92 92
Caudate nucleus 91 91
View Top Normal tissues
Compounds category icon Compounds
Score Help
Sirolimus 100 100
Nchembio790-comp36 100 100
W01300000 99 99
Bactopeptone 99 99
Fhpi 82 82
U 0126 80 80
View Top Compounds
Diseases category icon Diseases
Score Help
Cardiac arrhythmia 100 100
Postpartum cardiomyo… 94 94
Fracture of femur 90 90
Ischemic reperfusion… 81 81
Helicobacter-associa… 78 78
Obesity 75 75
View Top Diseases

Individual Studies

  • Drug target sets for approved compounds

    score: 100100 | Homo sapiens Homo sapiens | Therapeutic   Therapeutic

    The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information.

    Authors: David S Wishart, Craig Knox, An Chi Guo et al.

    Organization: Department of Computing Science, Univers…

  • SCC7 and NR-S1 murine tumors after C-ion or gamma irradiation

    score: 9999 | Mus musculus Mus musculus | RNA Expression   RNA Expression

    C3H/HeMs male mice were irradiated by gamma-rays (30Gy, 50Gy, 70Gy) or carbon ions (30Gy) as local irradiation in single doses to hind legs where each tumor was transplanted.

    Authors: Nojiri Kazunori, Iwakawa Mayumi, Imadome Kaori et al.

    Organization: National Institute of Radiological Scien…
View All Individual Studies

Associated Researchers

Help for Associated Researchers

Thought leaders and organizations working on research involving mTOR.

View All Author iconAuthors
  • Charles A Hoeffer
  • David M Sabatini
  • Sara C Kozma
  • George V Thomas
  • Jonathan D Powell
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • Ariad Pharmaceuticals
  • Mayo Clinic
  • M.D. Anderson Cancer Center
  • Exelixis
  • University of Utah
View All Affiliations icon Organizations
  • University of California
  • Harvard Medical School
  • Novartis Institutes for BioMedical Research
  • St. Jude Children's Research Hospital
  • University of Basel

Clinical Trials | 278 trials

Help for Clinical Trials View All

Community

Help for Community
View All NextBio Users | 3 people
NextBio Groups

  • No NextBio groups were found for “mTOR”.
    Be the first to start a group and share your interests with others within the NextBio community.

© 2010 NextBio