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Any of a group of related cytoplasmic, membrane bound organelles that are found in most animal cells and that contain a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.

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Data Correlations | 2,863 studies

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Tissues category icon Normal tissues
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Vermis of cerebellum 100 100
Hemisphere of cerebe… 98 98
Mesenteric lymph nod… 91 91
Nucleus accumbens 90 90
Putamen 89 89
Caudate nucleus 88 88
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Compounds category icon Compounds
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Visudyne 100 100
Adeka Pluronic F 108 98 98
Transferrin 92 92
Matrigel 91 91
Ornithine 90 90
Gsh 88 88
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Diseases category icon Diseases
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Infertility due to a… 100 100
Common acute lymphob… 92 92
Pre B-cell acute lym… 92 92
Hodgkin disease, nod… 91 91
Acute monocytic leuk… 89 89
Primary cutaneous di… 87 87
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Individual Studies

  • Testis from interspecific recombinant mice

    score: 100100 | Mus musculus Mus musculus | RNA Expression   RNA Expression

    Analysis of the genomic expression profiles in interspecific recombinant congenic strains starting from a cross between Mus musculus and mus spretus.

    Source: NextBio Library/Atlas - Organs, tissues and cell types

  • Gene expression profiling induced by overexpression and silencing of Ankrd2

    score: 9696 | Mus musculus Mus musculus | RNA Expression   RNA Expression

    Ankrd2 is a member of the Muscle Ankyrin Repeat Protein family (MARPs). We produced and examined both morphological and functional features of myocytes stable overexpressing or silencing the Ankrd2 protein.

    Authors: Bean C, Facchinello N, Salamon M et al.

    Organization: University of Padova CRIBI - Biotechnolo…
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Associated Researchers

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Thought leaders and organizations working on research involving lysosome.

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  • Marja Jäättelä
  • Keiji Tanaka
  • Xuetao Cao
  • Antony Galione
  • Jesper Nylandsted
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • Genzyme
  • Eunice Kennedy Shriver National Institute of Child Health and Human De…
  • Zymenex A/S
  • National Institute of Neurological Disorders and Stroke (NINDS)
  • ExSAR Corporation
View All Affiliations icon Organizations
  • Institute of Cancer Biology
  • University of Texas Southwestern Medical Center
  • Weill Medical College of Cornell University
  • Washington University School of Medicine
  • University of Messina

Community

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