lysophosphatidic acid

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Search Term: lysophosphatidic acid (treatment)

Overview

Molecular weight:	436.52 g/mol
Molecular formula:	C₂₁H₄₁O₇P

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Data Correlations | 2 studies

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Genes

Score

1700012E03Rik

100

Itgb2l

Hbb-b1

MUM1

2010110K18Rik

APOL3

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Biogroups

Score

Ribosome

100

Polynucleotidyl transferase, Ribonu…

Lysine Biosynthesis

Alkaloid Biosynthesis II

Biotin Metabolism

I17 - mucus peptidase inhibitor inh…

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Individual Studies
B Cell Response to Short-Term Stimulation with 33 Single Ligands Mus musculus \| RNA Expression Major Patterns of B Cell Gene Expression Changes in Response to Short-Term Stimulation with 33 Single Ligands Authors: Hart Rebecca, Chang Mi Sook, Kim Jong-Woo et al. Organization: California Institute of Technology Biolo…	Mammary tumors from mice overexpressing ATX, LPA1, LPA2, or LPA3 in mammary epithelium Mus musculus \| RNA Expression Mammary tumors formed in mice transgenically expressing human ATX, LPA1, LPA2 or LPA3 in the mammary epithelium were compared to the whole mouse Source: NextBio Library/Oncology

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Literature | 2,811 results

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Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs.

Authors: Hidenobu Kanda, Rebecca Newton, Russell Klein, Yuka Morita, Michael D Gunn, Steven D Rosen
Nature immunology 2008 Apr
Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases.

Authors: Shuying Liu, Makiko Umezu-Goto, Mandi Murph, Yiling Lu, Wenbin Liu, Fan Zhang, Shuangxing Yu, L Clifton Stephens, Xiaojiang Cui, George Murrow,…
Cancer cell 2009 Jun 2

Associated Researchers

Thought leaders and organizations working on research involving lysophosphatidic acid.

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Authors

Jerold Chun
Gabor Tigyi
Ryoko Tsukahara
Glenn D Prestwich
Gordon B Mills

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Clinical Trials Sponsors

National Cancer Institute (NCI)
Case Comprehensive Cancer Center

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Organizations

Lerner Research Institute
University of Texas M.D. Anderson Cancer Center
Helen L. Dorris Child and Adolescent Neuropsychiatric Disorder Institu…
Massachusetts General Hospital
University of Chicago

Clinical Trials | 2 trials

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Protein Evaluation in Patients With Stage III or Stage IV Primary Peritoneal or Fallopian Tube Cancer or Stage II, Stage III, or Stage IV Ovarian Epithelial Cancer in Remission

conditions: Fallopian Tube Cancer ; Ovarian Cancer ; Peritoneal Cavity Cancer

interventions: proteomic profiling ; laboratory biomarker analysis ; surface-enhanced laser desorption/ionization-time of flight mass spectrometry ; diagnostic imaging
Study of Tumor Samples in Patients Undergoing Radiation Therapy or Surgery For Primary Melanoma of the Eye

conditions: Intraocular Melanoma

interventions: fluorescence in situ hybridization ; laboratory biomarker analysis ; fine-needle aspiration ; therapeutic conventional surgery ; radiation therapy

News | 1 story

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Bioactive lipid LPA mediates fibrogenesis in bleomycin mouse model of scleroderma
News-Medical. - February 10, 2010

Community

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NextBio Users | 3 people

Jennifer Hurst-Kennedy

Jing zhang
Graduate Student

Harvard University

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