A chronic inflammatory connective tissue disease marked by skin rashes, joint pain and swelling, inflammation of the kidneys, inflammation of the fibrous tissue surrounding the heart (i.e., the pericardium), as well as other problems. Not all affected individuals display all of these problems. Also called systemic lupus erythematosus.

Data Correlations | 9 studies

View All

Genes	Score
FCGR2A	100
GADD45A	100
CDKN1A	100
RASGRP1	100
FAS	100
DEF6	100

View Top Genes

Biogroups	Score
Cell Cycle	100
Hematopoietic Cell Lineage	100
Hemoglobin's Chaperone	99
Immunoglobulin Protein Family	98
Immunoglobulin subtype	98
Cytokine Cytokine Receptor Interact…	98

View Top Biogroups

Individual Studies

Mouse Phenotypes - Autoimmune disease Mus musculus |   Mutations/Phenotypic This study contains curated mouse gene mutation data extracted from the Mouse Genome Database (MGD) at The Jackson Laboratory, Bar Harbor, Maine. Additional computational processing and curation of mouse phenotype data was performed to further organize and group data from related phenotypes into uni… Source: NextBio Library/Mutation and Phenotypic data

Congenic strains containing overlapping BXSB intervals reveal novel lupus candidate genes Mus musculus |   RNA Expression To probe the genetic basis of systemic lupus erythematosus in BXSB mice, several congenic strains of mice were profiled by microarray. Source: NextBio Library/Immune response and infection

View All Individual Studies

Literature | 49,550 results

View All

• Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus.

  Authors: Robert R Graham, Chris Cotsapas, Leela Davies, Rachel Hackett, Christopher J Lessard, Joanlise M Leon, Noel P Burtt, Candace Guiducci, Melissa Parkin, Casey Gates,…

  Nature genetics 2008 Sep

• The role of complement in the development of systemic lupus erythematosus.

  Authors: Anthony P Manderson, Marina Botto, Mark J Walport

  Annual review of immunology 2004

Associated Researchers

Thought leaders and organizations working on research involving lupus erythematosus.

View All Authors

• Timothy W Behrens
• Marta E Alarcón-Riquelme
• Peter K Gregersen
• Timothy J Vyse
• Lindsey A Criswell

View All Clinical Trials Sponsors

• National Institute of Arthritis and Musculoskeletal and Skin Diseases …
• National Center for Research Resources (NCRR)
• Genentech
• Kuhn, Annegret
• National Institute of Allergy and Infectious Diseases (NIAID)

View All Organizations

• Oklahoma Medical Research Foundation
• Beth Israel Deaconess Medical Center
• Broad Institute of Harvard and Massachusetts Institute of Technology
• University of California
• University of Manchester

Clinical Trials | 790 trials

View All

• Cutaneous Lupus Erythematosus and Elidel

  conditions: Lupus Erythematosus, Cutaneous ; Lupus Erythematosus, Discoid

  interventions: Elidel (pimecrolimus)

   

• European Society of Cutaneous Lupus Erythematosus (EUSCLE)

  conditions: Lupus Erythematosus, Cutaneous ; Lupus Erythematosus, Systemic

  interventions: laboratory analysis

   

News | 79 stories

View All

• Bharatbook.com : Systemic Lupus Erythematosus - Drug Pipeline Analysis

  PR-inside.com. - December 25, 2009

• Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus [LETTERS]

  Genome Research. - February 01, 2010

Community

View All NextBio Users | 5 people

• Yves  Renaudineau

  Associate professor

  Brest University Medical School

• Shiuh-Bin  Fang

  Dr

  Centre for Paediatric Gastroenterology, Royal Free & University College Medical School

NextBio Groups

• No NextBio groups were found for “lupus erythematosus”.
  Be the first to start a group and share your interests with others within the NextBio community.

search → result

search → result