Functional and Genomic Profiling of Effector CD8 T Cell Subsets

Mus musculus

Using killer cell lectin-like receptor G1 as a marker to distinguish terminal effector cells from memory precursors, we found that despite their diverse cell fates both subsets possessed remarkably similar gene expression profiles and functioned as equally potent killer cells. However, only the memo…

Organization: Emory University Emory University School…

Total # Biosets: 6

Murine memory B cells compared to naive

Mus musculus

Using model systems that help overcome the lack of murine memory-specific markers and the low frequency of antigen-specific memory and naïve cells, we undertook a global comparison of gene expression between memory B cells and their naive precursors.

Authors: Tomayko M Mary, Shlomchik J Mark

Organization: Yale University Dermatology Mark J. Shlo…

Total # Biosets: 1