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acidosis caused by accumulation of lactic acid more rapidly than it can be metabolized; may occur spontaneously or in association with diseases such as diabetes mellitus, leukemia, or liver failure.

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Data Correlations | 3 studies

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Genes category icon Genes
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SUCLG1 100 100
PDHA1 100 100
DLD 100 100
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Biogroups category icon Biogroups
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Citrate Cycle 100 100
Acetylcholine Synthesis 95 95
Pyruvate Metabolism 91 91
Glycolysis and Gluconeogenesis 91 91
Valine Leucine and Isoleucine Biosy… 91 91
Malate Pathway 90 90
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Individual Studies

  • Skeletal muscle expression profiling in mitochondrial disorders

    Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    We studied the gene expression profile of muscle tissue biopsies obtained from 12 Mitochondrial Encephalomyopathy Disorder (MED) patients compared with age-matched healthy individuals.

    Authors: Crimi Marco, Comi P Giacomo

    Organization: University of Milan Dept. of Neuroscienc…

  • OMIM - Lactic acidosis

    Homo sapiens Homo sapiens | Mutations/Phenotypic   Mutations/Phenotypic

    This study contains curated human phenotype data extracted from OMIM. Additional computational processing and curation of the phenotype data was performed to further organize and group data from related phenotypes into unifying disease categories.

    Source: NextBio Library/Mutation and Phenotypic data
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Associated Researchers

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Thought leaders and organizations working on research involving lactic acidosis.

View All Author iconAuthors
  • Massimo Zeviani
  • Peter W Stacpoole
  • Edward Valenstein
  • Douglas A Richards
  • Nick Murphy
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • National Institute of Allergy and Infectious Diseases (NIAID)
  • FDA Office of Orphan Products Development
  • National Center for Research Resources (NCRR)
  • University Health Network, Toronto
  • Hartford Hospital
View All Affiliations icon Organizations
  • University of Illinois College of Medicine at Chicago
  • University Hospital Birmingham NHS Trust
  • Columbia University
  • University of Pittsburgh
  • National University Hospital

Clinical Trials | 75 trials

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