Murine liver after treatment for 2 weeks with various carcinogens and non-carcinogens

Mus musculus |   RNA Expression

In this study we used oligonucleotide microarray analysis to identify genes that were up- or downregulated in mouse liver early after treatment with different known carcinogens, including oxazepam, o-nitrotoluene and methyleugenol, or the non-carcinogens p-nitrotoluene, eugenol and acetaminophen.

Source: NextBio Library/Pharmacology and Toxicology

Liver Pharmacology and Xenobiotic Response Repertoire

Rattus norvegicus |   RNA Expression

A definition of RNA expression changes that correlate with liver response programs and an understanding of the similarities and differences in responses to different classes of chemicals would aid in new chemical or drug characterization and add to our understanding of liver biology.

Authors: Natsoulis G, Pearson CI, Gollub J et al.

Organization: Iconix Biosciences 325 E. Middlefield Rd…