A primary or metastatic malignant tumor involving the small intestine, large intestine, or both. Representative examples are carcinomas, lymphomas, and sarcomas. -- 2004

Data Correlations | 58 studies

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Genes	Score
SLC26A3	100
SMAD4	100
PLA2G2A	100
AXIN2	100
CTNNB1	100
DLC1	100

View Top Genes

Biogroups	Score
Focal Adhesion	100
Cell Communication	99
EGF-like region, conserved site	99
All Peptidase Inhibitors	99
ECM Receptor Interaction	98
Leukocyte Transendothelial Migratio…	98

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Individual Studies

Diet-influenced colon tumorigenesis Rattus norvegicus |   RNA Expression We previously reported that lifetime consumption of soy proteins or whey proteins reduced the incidence of azoxymethane (AOM)-induced colon tumors in rats. To obtain insights into these effects, global gene expression profiles of colons from rats with lifetime ingestion of casein (CAS, control diet)… Authors: Xiao R, Badger TM, Simmen FA Organization: Nutrition Center, Arkansas Chidren's Hos…

Microsatellite instability in colorectal cancers Homo sapiens |   RNA Expression Samples were taken from colorectal cancers in surgically resected specimens in 84 colorectal cancer patients. The expression profiles were determined using Affymetrix Human Genome U133 Plus 2.0 arrays. Comparison between the sample groups allow to identify a set of discriminating genes between MSI a… Authors: Watanabe T, Kobunai T, Toda E et al. Organization: University of Tokyo Department of Surgic…

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Literature | 27,656 results

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• Crypt stem cells as the cells-of-origin of intestinal cancer.

  Authors: Nick Barker, Rachel A Ridgway, Johan H van Es, Marc van de Wetering, Harry Begthel, Maaike van den Born, Esther Danenberg, Alan R Clarke, Owen J Sansom, Hans Clevers

  Nature 2009 Jan 29

• Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development.

  Authors: Abdolrahman S Nateri, Bradley Spencer-Dene, Axel Behrens

  Nature 2005 Sep 8

Associated Researchers

Thought leaders and organizations working on research involving intestinal cancer.

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• Alan R Clarke
• Owen J Sansom
• Hans Clevers
• N Mandir
• Albert R Hollenbeck

View All Clinical Trials Sponsors

• Chinese University of Hong Kong
• Hokkaido Gastrointestinal Cancer Study Group
• Fred Hutchinson Cancer Research Center
• Burzynski Research Institute
• European Institute of Oncology

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• Cardiff University
• National Cancer Institute
• Josephine Nefkens Institute
• State University of New Jersey
• London Research Institute

Clinical Trials | 518 trials

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• Balance System Study in Type 2 Diabetic Patients

  conditions: Type 2 Diabetes ; Obesity

  interventions: BALANCE System intestinal electrical stimulator

   

• Selective COX-II Inhibitor as an Adjuvant Therapy in Patients With Resectable Advanced Stomach Cancer ( Histological Staging ≥ T2N1) - A Multi-Centre Prospective Randomised Controlled Trial

  conditions: Cancer of Stomach

  interventions: Oral Vioxx (Rofecoxib)

   

News | 82 stories

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• Gene offers bowel cancer 'shield'

  BBC. - November 24, 2009

• Study ties saturated fat to small intestine cancer

  MSNBC. - November 21, 2008

Community

View All NextBio Users | 4 people

• Jin Boo  Jeong

• Ian  Kasman

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