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Syndromes in which there is a deficiency or defect in the mechanisms of immunity, either cellular or humoral.

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Data Correlations | 25 studies

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Genes category icon Genes
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CXCR4 100 100
ITGB2 100 100
ADA 100 100
ATM 100 100
CYBB 100 100
BLM 100 100
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Biogroups category icon Biogroups
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Hematopoietic Cell Lineage 100 100
Cytokine Cytokine Receptor Interact… 100 100
IL-7 Pathway 99 99
Antigen Processing and Presentation 98 98
CTL Mediated Immune Response Agains… 98 98
Calcineurin Nf At Signaling 98 98
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Individual Studies

  • Early response of H69 xenograft tumors following Photodynamic Therapy (PDT)

    Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    The response of tumors to PDT treatment is expected to provide information on effects of oxygen depletion, induced apoptosis, induction of an inflammatory response and induction of an ani-tumor immune response.

    Authors: Starkey R Jean, Rebane Alexsander, Drobizhev A Mikhail et al.

    Organization: Montana State University Microbiology Fu…

  • DNA methyltransferase 3B mutations in ICF syndrome

    Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    Genome-wide DNA methylation patterns are established and maintained by the coordinated action of three DNA methyltransferases, DNMT1, DNMT3A, and DNMT3B. DNMT3B hypomorphic germline mutations are responsible for two-thirds of Immunodeficiency, Centromere Instability, Facial Anomalies (ICF) syndrome …

    Authors: Robertson D Keith, Jin Bilian

    Organization: University of Florida 1601 SW Archer Roa…
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Associated Researchers

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Thought leaders and organizations working on research involving immunodeficiency.

View All Author iconAuthors
  • Alain Fischer
  • Guido Silvestri
  • Christoph Klein
  • Jörn E Schmitz
  • Ivona Pandrea
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • National Institute of Allergy and Infectious Diseases (NIAID)
  • National Human Genome Research Institute (NHGRI)
  • National Cancer Institute (NCI)
  • Boehringer Ingelheim Pharmaceuticals
  • Baxter Healthcare Corporation
View All Affiliations icon Organizations
  • University of Tennessee College of Medicine
  • University of Alabama - Birmingham
  • National Institute of Allergy and Infectious Diseases
  • Institut National de la Santé et de la Recherche Médicale U429
  • Hôpital Necker-Enfants Malades

Clinical Trials | 3,663 trials

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