hypercalcaemia(Hypercalcemia) - NextBio

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Search Term: hypercalcaemia (disease: Hypercalcemia)

Overview

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Abnormally high concentration of calcium in the peripheral blood. -- 2004

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Data Correlations | 4 studies

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Genes category icon

Score

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100

100

94

89

86

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Metabotropic Glutamate Pheromone

100

100

99

Extracellular ligand-binding recept…

98

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Individual Studies

Parathyroid hormone-related protein in breast cancer

Homo sapiens | RNA Expression

Parathyroid hormone-related protein (PTHrP) is overexpressed in many cancer types. This secretory protein can induce hypercalcaemia of malignancy by mimicking the action of calcium-regulating parathyroid hormone (PTH). PTHrP may also be involved in the regulation of migration, invasion, proliferatio…

Authors: Dittmer J, Campbell P

Organization: University of Halle Clinic of Gynecology…

Mouse Phenotypes - Metabolic disease

Mus musculus | Mutations/Phenotypic

This study contains curated mouse gene mutation data extracted from the Mouse Genome Database (MGD) at The Jackson Laboratory, Bar Harbor, Maine. Additional computational processing and curation of mouse phenotype data was performed to further organize and group data from related phenotypes into uni…

Source: NextBio Library/Mutation and Phenotypic data

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Literature | 17,109 results

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Multiple endocrine neoplasia type 1 knockout mice develop parathyroid, pancreatic, pituitary and adrenal tumours with hypercalcaemia, hypophosphataemia and hypercorticosteronaemia.

Authors: Brian Harding, Manuel C Lemos, Anita A C Reed, Gerard V Walls, Jeshmi Jeyabalan, Michael R Bowl, Hilda Tateossian, Nicky Sullivan, Tertius Hough, William D Fraser,…
Endocrine-related cancer 2009 Dec
Narrative review: furosemide for hypercalcemia: an unproven yet common practice.

Authors: Susan B LeGrand, Dona Leskuski, Ivan Zama
Annals of internal medicine 2008 Aug 19

Associated Researchers

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Thought leaders and organizations working on research involving hypercalcaemia.

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R F Miller
R E Toribio
Rajesh V Thakker
T J Rosol
R A Ferrand

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Clinical Trials Sponsors

Amgen
LEO Pharma
University of Wisconsin, Madison
National Institute of Diabetes and Digestive and Kidney Diseases (NIDD…
Abbott

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University of Oxford
Ohio State University
Royal Free Hospital
University College London Hospitals
Royal Victoria Infirmary

Clinical Trials | 599 trials

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Study of 1.25 Mmol/L Calcium Dialysate on Mineral Metabolism in Haemodialysis Patients.

conditions: Hyperparathyroidism ; Hypercalcemia

interventions: physiological (1.25 mmol/L ) calcium dialysate
Zometa for the Management of Tumor-induced Hypercalcemia and Malignant Bone Pain in the Community

conditions: Cancer ; Hypercalcemia ; Pain

interventions: Zoledronic acid (Zometa)

News | 6 stories

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Severe Hypercalcemia Secondary to Factitious Thyrotoxicosis
American journal. - January 31, 2010
Health Matters : What is Hypercalcemia Secondary to Cancer ?
PR-inside.com. - November 06, 2009

Community

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NextBio Users | 1 person

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