histidine ammonia-lyase

Histidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids [provided by RefSeq]

Data Correlations | 1,053 studies

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Normal tissues	Score
Vulva	100
Penis	98
Epidermis	93
Set of fingers	93
Fetal organ	92
Nipple	88

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Compounds	Score
Glycopyrrolate	100
Repaglinide	95
Sodium Dioxoarsenate	82
Zinc Ion	78
Zinc00394284	75
Folic Acid (tn)	74

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Diseases	Score
Deficiency of histid…	100
Acute myeloid leukem…	60
Papilloma of skin	58
Lepromatous leprosy	56
Leprosy reversal rea…	55
Neoplasm of liver	50

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Individual Studies
OMIM - Congenital disorder score: 100 | Homo sapiens |   Mutations/Phenotypic This study contains curated human phenotype data extracted from OMIM. Additional computational processing and curation of the phenotype data was performed to further organize and group data from related phenotypes into unifying disease categories. Source: NextBio Library/Mutation and Phenotypic data	Hepatocellular carcinomas with hepatitis C virus etiology score: 100 | Homo sapiens |   RNA Expression To characterize the genetic alterations that instigate hepatitis C virus-induced hepatocellular carcinoma (HCC), we conducted an integrative genomic analysis of 91 HCCs. Source: NextBio Library/Oncology

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Literature | 148,909 results

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• The unexpected origin of plasmaspheric hiss from discrete chorus emissions.

  Authors: Jacob Bortnik, Richard M Thorne, Nigel P Meredith

  Nature 2008 Mar 6

• Darwin respected by his religious contemporaries.

  Authors: R J Berry

  Nature 2009 Nov 26

Associated Researchers

Thought leaders and organizations working on research involving his.

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• Nancy E Cooke
• Stephen A Liebhaber
• Yugong Ho
• M Guthoff
• Vikas Nanda

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• University of California
• University of Pennsylvania School of Medicine
• University of Oxford
• Universität Duisburg-Essen
• Nagoya City University School of Nursing

Community

View All NextBio Users | 10 people

• Daniel  Jurczak

• Vladimir  Lerner

  Professor

  Ben Gurion University of the Negev

View All NextBio Groups | 2 groups

• Leuprorelin Acetate CAS NO 53714-56-0

  1 members

• Personalized Medicine

  29 members

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