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Description: A colorless, odorless, viscous dihydroxy alcohol. It has a sweet taste, but is poisonous if ingested. Ethylene glycol is the most important glycol commercially available and is manufactured on a large scale in the United States. It is used as an antifreeze and coolant, in hydraulic fluids, and in the manufacture of low-freezing dynamites and resins. [PubChem]
Drug Type: Small Molecule; Experimental
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Data Correlations | 2 studies

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Genes category icon Genes
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PRSS27 100 100
ARHGEF1 89 89
NEUROD2 87 87
PTH 86 86
DFFA 85 85
HGF 85 85
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Biogroups category icon Biogroups
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I49 - proSAAS 100 100
HECT 99 99
Forkhead-associated 99 99
Immunoglobulin subtype 98 98
C2 calcium/lipid-binding region, Ca… 98 98
C2 calcium-dependent membrane targe… 98 98
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Individual Studies

  • Drug-Induced Renal Tubular Toxicity

    Rattus norvegicus Rattus norvegicus | RNA Expression   RNA Expression

    These data support the publication titled "A Gene Expression Signature that Predicts the Future Onset of Drug-Induced Renal Tubular Toxicity"

    Authors: Fielden MR, Eynon BP, Natsoulis G et al.

    Organization: Iconix Pharmaceuticals 325 E Middlefield…

  • Non-genotoxic Hepatocarcinogens (Iconix study)

    Rattus norvegicus Rattus norvegicus | RNA Expression   RNA Expression

    We have developed a short-term in vivo rat assay that predicts whether non-genotoxic chemicals are likely to induce hepatic tumors based on transcript profiles in the liver. Using a large independent test set, assay accuracy was found to be superior to existing pathological and genomic markers. Comp…

    Authors: Fielden MR, Brennan R, Gollub J

    Organization: Iconix Biosciences 325 E. Middlefield Rd…
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Associated Researchers

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Thought leaders and organizations working on research involving ethylene glycol.

View All Author iconAuthors
  • Alex A Aimetti
  • Kazunori Kataoka
  • H Dennis Tolley
  • Milton L Lee
  • Kristi S Anseth
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • Braintree Laboratories
  • Norgine
  • FDA Office of Orphan Products Development
  • Department of Veterans Affairs
  • Grünenthal GmbH
View All Affiliations icon Organizations
  • Brigham Young University
  • University of Colorado
  • Renal Research Institute
  • University of Kentucky
  • University of North Carolina at Chapel Hill

Clinical Trials | 114 trials

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News | 1 story

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Community

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View All NextBio Users | 2 people
  • No photo available Piotr  Nowak

    vice-manager, assistant

    Laboratory of Parasitology, District Sanitary-Epidemiological Center

  • Piotr Nowak Piotr  Nowak

    vice-manager/ assistant

    Laboratory of Parasitology of the District Sanitary-Epidemiological Center

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