Mouse Lung Tumors in Rodent Cancer Bioassays

Mus musculus |   RNA Expression

The primary goal of toxicology and safety testing is to identify agents that have the potential to cause adverse effects in humans. Unfortunately, many of these tests have not changed significantly in the past 30 years and most are inefficient, costly, and rely heavily on the use of animals. The r…

Authors: Thomas S Russell, Pluta J Linda, Yang Longlong et al.

Organization: The Hamner Institutes for Health Science…

Transcriptional Biomarkers to Predict Female Mouse Lung Tumors - A 26 Chemical Set

Mus musculus |   RNA Expression

Five-week-old female B6C3F1 mice were exposed for 13 weeks to 26 chemicals. With each chemical treatment, a matched vehicle control group was run concurrently with the exposure. Microarray analysis was performed on the lungs of three to four mice per treatment group

Source: NextBio Library/Oncology