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Thickening and loss of elasticity of the CORONARY ARTERIES, leading to progressive arterial insufficiency (CORONARY DISEASE).

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Data Correlations | 7 studies

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Genes category icon Genes
Score Help
CD36 100 100
387573 100 100
338334 100 100
387584 100 100
387585 100 100
CHD5 100 100
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Biogroups category icon Biogroups
Score Help
Small chemokine, interleukin-8-like 100 100
Cytokine Cytokine Receptor Interact… 96 96
NO2-dependent IL 12 Pathway in NK c… 96 96
Toll-like Receptor Signaling Pathwa… 94 94
Complement and Coagulation Cascades 94 94
Interferon Gamma Pathway 94 94
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Individual Studies

  • Myocardial remodeling in response to left ventricular assist device (LVAD) implant

    Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    19 paired human left ventricular apex samples were harvested at the time of implant of a left ventricular assist device (PRE) and at the time of explant (POST). The cohort included patients that were clinically classified as "ischemic" (I) showing evidence of coronary artery disease, "non-ischemic" …

    Authors: Hall J, Grindle SM, Han X et al.

    Organization: Lillehei Heart Institute Division of Car…

  • Simvastatin treatment of HPBM-macrophages

    Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    HMG-CoA reductase inhibitors, statins, have beneficial vascular effects beyond their cholesterol-lowering action. These pleiotropic effects include an anti-inflammatory effect on macrophages. Since macrophages play a central role in atherogenesis, we further characterized the effects on peripheral b…

    Authors: Tuomisto T Tiina, Lumivuori Henri, Kansanen Emilia et al.

    Organization: A.I.Virtanen Institute Molecular Medicin…
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Associated Researchers

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Thought leaders and organizations working on research involving coronary atherosclerosis.

View All Author iconAuthors
  • Steven E Nissen
  • E Murat Tuzcu
  • Stephen J Nicholls
  • Raimund Erbel
  • Paul Schoenhagen
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • National Heart, Lung, and Blood Institute (NHLBI)
  • Seoul National University Bundang Hospital
  • TCA Cellular Therapy
  • Sanofi-Aventis
  • Assistance Publique - Hôpitaux de Paris
View All Affiliations icon Organizations
  • Cleveland Clinic
  • University of Duisburg-Essen
  • Mayo Clinic
  • Cleveland Clinic Foundation
  • Vorarlberg Institute for Vascular Investigation and Treatment

Clinical Trials | 629 trials

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Community

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