Integrated stress response of mouse fibroblast cell

Mus musculus

Comparison of genes induced during activation of the Integrated Stress Response by tunicamycin or following AP20187 induced dimerization of a Fv2E-PERK chimera in wildtype cells and cells carrying mutations in key ISR signaling molecules.

Authors: Lu PD, Jousse C, Marciniak SJ, Zhang Y, Novoa I, Scheuner D et al.

Organization: NYU School of Medicine Pharmacology 540 …

Total # Biosets: 7

RNAi knock down of endogenous genes in HeLa cells

Homo sapiens

Microarray analysis of cells transfected with siRNAs having seeds with low, medium, or high seed complement frequencies (SCFs)to understand the association between seed sequences and off-target profiles.

Source: NextBio Library/Metabolic disorders and Obesity

Total # Biosets: 3