The survival and differentiation of granule cells in the brain is controlled by pro-growth PACAP and pro-apoptotic ceramides. Source Signaling Transduction KE. Link http://stke.sciencemag.org

Data Correlations | 1,894 studies

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Normal tissues	Score
Nipple	100
Vestibular nuclear c…	94
Inferior ganglion of…	94
Substantia nigra	89
Subthalamic nucleus	88
Midbrain	86

View Top Normal tissues

Compounds	Score
2-deoxyglucose	100
Nsc285166	85
Tropisetron	75
Alfacalcidol	73
Triacetin	73
Betas-crystallin	71

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Diseases	Score
Disuse atrophy	100
Tympanic membrane pe…	95
Ebola hemorrhagic fe…	91
Benign neoplasm of f…	88
Smallpox	87
Aggressive fibromato…	82

View Top Diseases

Individual Studies

Transcriptome modulation analysis of CMV-infected monocyte-derived dendritic cells score: 100 | Homo sapiens |   RNA Expression Immature monocyte-derived dendritic cells were generated from CMV neg healthy blood donors and infected or not with an endotheliotropic CMV strain. Gene expression modulation by the CMV infection was studied in a time course assay (non-infected - NI - vs 6h or 48h post-infection. Authors: Haspot Fabienne, Bihouée Audrey, Chevalier Catherine et al. Organization: INSERM UMR643 ITERT - CHU Hotel Dieu 30,…

Soleus and gastrocnemius muscle from freely ambulatory or hind-limb suspended rats score: 80 | Mus musculus |   RNA Expression Gene expression changes induced by acute skeletal muscle unloading was investigated by hind-limb suspension (HLS) treatment of mice. Authors: Mazzatti J Dawn, Smith A Melissa, Oita C Radu et al. Organization: Unilever Colworth Science Park Sharnbroo…

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Literature | 301,388 results

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• HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation.

  Authors: Nicolas Chomont, Mohamed El-Far, Petronela Ancuta, Lydie Trautmann, Francesco A Procopio, Bader Yassine-Diab, Geneviève Boucher, Mohamed-Rachid Boulassel, Georges Ghattas, Jason M Brenchley,…

  Nature medicine 2009 Aug

• Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival.

  Authors: Martin Schwickart, Xiaodong Huang, Jennie R Lill, Jinfeng Liu, Ronald Ferrando, Dorothy M French, Heather Maecker, Karen O'Rourke, Fernando Bazan, Jeffrey Eastham-Anderson,…

  Nature 2010 Jan 7

Associated Researchers

Thought leaders and organizations working on research involving cell survival.

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• Andreas Strasser
• Klaus Rajewsky
• Fabienne Mackay
• Takashi Matsui
• Vivek M Rangnekar

View All Clinical Trials Sponsors

• National Institute of Allergy and Infectious Diseases (NIAID)
• Infinity Pharmaceuticals
• National Cancer Institute (NCI)
• National Heart, Lung, and Blood Institute (NHLBI)
• DiaTech Oncology

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• Harvard Medical School
• University of Virginia
• McGill University
• Centre de Recherche du Centre Hospitalier de l'Université de Montréal …
• Research Institute of Molecular Pathology

Clinical Trials | 8,746 trials

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• Red Blood Cell (RBC) Survival Following Transfusion in Infants

  conditions: Neonatal Anemia

  interventions: Transfused Biotin RBCs

   

• Clinical Importance of Treating Iron Overload in Sickle Cell Disease

  conditions: Anemia, Sickle Cell ; Transfusion Hemochromatosis

  interventions: deferasirox

   

News | 205 stories

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• New understanding of CD44 receptor's role in immune cell survival

  News-Medical. - January 29, 2010

• Secrets of immunologic memory: New understanding of CD44 receptor's role in immune cell survival

  Science Daily. - January 27, 2010

Community

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• Jennifer  Hurst-Kennedy

• Mohammad  Heydarian

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• Breast Cancer Integrated Knowledge Group

  26 members

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