cell cycle checkpoints - NextBio

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Search Term: cell cycle checkpoints

Overview

Data Correlations | 10 studies

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Individual Studies

Ionizing radiation-damaged human fibroblasts

Homo sapiens

Cell cycle arrest and stereotypic transcriptional responses to DNA damage induced by ionizing radiation (IR) were quantified in telomerase-expressing human diploid fibroblasts.

Authors: Zhou Tong, Chou Jeff, Kaufmann William

Organization: University of North Carolina at Chapel H…

Total # Biosets: 14

Wild type yeast, mre11delta, rad50delta, and spo11Y135F at meiosis

Saccharomyces cerevisiae

Mre11, together with Rad50 and Xrs2/NBS, plays pivotal roles in homologous recombination, repair of DNA double strand breaks (DSBs), activation of damage-induced checkpoint, and telomere maintenance. Using DNA microarray assays to analyze yeast mutants (mre11delta, rad50delta, and spo11Y135F) defect…

Authors: Kugou Kazuto, Sasanuma Hiroyuki, Matsumoto Kouji, Shirahige Katsuhiko, Ohta Kunihiro

Organization: RIKEN Shibata Distinguished Scientist La…

Total # Biosets: 2

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Literature | 8,960 results

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tRNA traffic meets a cell-cycle checkpoint.

Authors: Ted Weinert, Anita K Hopper
Cell 2007 Nov 30
Distinct mitochondrial retrograde signals control the G1-S cell cycle checkpoint.

Authors: Edward Owusu-Ansah, Amir Yavari, Sudip Mandal, Utpal Banerjee
Nature genetics 2008 Mar

Associated Researchers

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Thought leaders and organizations working on research involving cell cycle checkpoints.

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Beth A Helmink
Barry P Sleckman
Michael B Yaffe
Jiri Bartek
Claus Storgaard Sørensen

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Clinical Trials Sponsors

Christie Hospital NHS Foundation Trust
ArQule
National Cancer Institute (NCI)

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Affiliations icon

University of Texas M.D. Anderson Cancer Center
University of California
Washington University School of Medicine
Yale University School of Medicine
University of Massachusetts Medical School

Clinical Trials | 3 trials

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DNA Analysis in Predicting Lung Cancer Risk

conditions: Lung Cancer

interventions: gene expression analysis ; mutation analysis ; polymorphism analysis ; proteomic profiling ; laboratory biomarker analysis ; questionnaire administration ; evaluation of cancer risk factors
An Exploratory Biomarker Study of ARQ 501 in Patients With Advanced Solid Tumors

conditions: Advanced Solid Tumors

interventions: ARQ 501

Community

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NextBio Users | 2 people

Adam Freund
Graduate Student

UC Berkeley

Justin Rains
BS

Northwestern State University of Louisiana

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