Partial or complete opacity of the crystalline lens of one or both eyes that decreases visual acuity and eventually results in blindness. Some cataracts appear in infancy or in childhood, but most develop in older individuals. (Diagnostic Surgical Pathology, 3rd ed.)

Data Correlations | 3 studies

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Genes	Score
CRYGD	100
GJA3	91
CRYBB2	90
CRYGC	87
493862	85
LIM2	83

View Top Genes

Biogroups	Score
Cell Communication	100
Keratin, type I	91
PMP-22/EMP/MP20/Claudin	90
Homeodomain-related	89
Filament	89
Homeobox Protein Family	89

View Top Biogroups

Individual Studies

Mouse Phenotypes - Cataract Mus musculus |   Mutations/Phenotypic This study contains curated mouse gene mutation data extracted from the Mouse Genome Database (MGD) at The Jackson Laboratory, Bar Harbor, Maine. Additional computational processing and curation of mouse phenotype data was performed to further organize and group data from related phenotypes into uni… Source: NextBio Library/Mutation and Phenotypic data

OMIM - Cataract Homo sapiens |   Mutations/Phenotypic This study contains curated human phenotype data extracted from OMIM. Additional computational processing and curation of the phenotype data was performed to further organize and group data from related phenotypes into unifying disease categories. Source: NextBio Library/Mutation and Phenotypic data

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Literature | 99,335 results

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• Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen.

  Authors: Antoni Hurtado, Kelly A Holmes, Timothy R Geistlinger, Iain R Hutcheson, Robert I Nicholson, Myles Brown, Jie Jiang, William J Howat, Simak Ali, Jason S Carroll

  Nature 2008 Dec 4

• Deficiency of hyccin, a newly identified membrane protein, causes hypomyelination and congenital cataract.

  Authors: Federico Zara, Roberta Biancheri, Claudio Bruno, Laura Bordo, Stefania Assereto, Elisabetta Gazzerro, Federica Sotgia, Xiao Bo Wang, Stefania Gianotti, Silvia Stringara,…

  Nature genetics 2006 Oct

Associated Researchers

Thought leaders and organizations working on research involving cataract.

View All Authors

• Xiaohua Gong
• Chun-hong Xia
• Shigekazu Nagata
• Dennis S C Lam
• Adam M DeRosa

View All Clinical Trials Sponsors

• National Eye Institute (NEI)
• Alcon Research
• Innovative Medical
• Indiana University School of Medicine
• Hospital Hietzing

View All Organizations

• UCL Institute of Ophthalmology
• Chinese University of Hong Kong
• Cambridge Research Institute
• G. Gaslini Institute and University of Genova
• Peking University Health Science Center

Clinical Trials | 781 trials

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• The Influence of Vision on Balance, Gait and Falls

  conditions: Cataract

  interventions: Cataract surgery

   

• Influence of Two Different Preloaded Intraocular Lens (IOLs) on Posterior Capsule Opacification

  conditions: Cataract

  interventions: cataract surgery

   

News | 102 stories

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• Cataracts From Antidepressants?

  WebMD. - March 12, 2010

• Health Matters : What is a Cataract ?

  PR-inside.com. - November 03, 2009

Community

View All NextBio Users | 7 people

• Bhagwat  Alapure

  Post Doctoral fellow (DRDO)

  Iladevi Cataract & IOL Research centre(ICIRC)

• Siamak  Zarei-Ghanavati

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