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A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

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Data Correlations | 4 studies

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Genes category icon Genes
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MAFD2 100 100
MAFD1 100 100
SLC6A3 100 100
XBP1 100 100
SST 100 100
ATP6V1A 97 97
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Biogroups category icon Biogroups
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chr16q13 100 100
chryq11 99 99
Ran Pathway 98 98
chr4q25 98 98
chr9q22 98 98
Growth factor, cystine knot 97 97
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Individual Studies

  • Adult postmortem brain tissue (dorsolateral prefrontal cortex) from bipolar disorder

    Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    Bipolar affective disorder is a severe psychiatric disorder with a strong genetic component but unknown pathophysiology. We used microarray technology (Affymetrix HG-U133A GeneChips) to determine the expression of approximately 22 000 mRNA transcripts in post-mortem brain tissue (dorsolateral prefro…

    Authors: Bahn S, Ryan MM, Lockstone HE et al.

    Organization: Cambridge Centre for Neuropsychiatric Re…

  • Human adult postmortem brain tissue from subjects with bipolar disorder

    Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    Bipolar affective disorder is a severe psychiatric disorder with a strong genetic component but unknown pathophysiology. We determined the expression of approximately 22 000 mRNA transcripts in post-mortem brain tissue (dorsolateral prefrontal cortex and orbitofrontal cortex) from patients with bipo…

    Authors: Bahn S, Ryan MM, Lockstone HE et al.

    Organization: University of Cambridge Cambridge Centre…
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Associated Researchers

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Thought leaders and organizations working on research involving bipolar disorder.

View All Author iconAuthors
  • Michael C O'Donovan
  • Pamela Sklar
  • Michael J Owen
  • Nick Craddock
  • Willem A Nolen
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • National Institute of Mental Health (NIMH)
  • Massachusetts General Hospital
  • GlaxoSmithKline
  • North Shore Long Island Jewish Health System
  • University of Pittsburgh
View All Affiliations icon Organizations
  • Massachusetts General Hospital
  • University of Edinburgh
  • Karolinska Institutet
  • Brain Science Institute
  • Erasmus Medical Center

Clinical Trials | 2,517 trials

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News | 52 stories

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Community

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