The process by which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of nutrient limitation and remodeling the intracellular structure for cell differentiation.

Data Correlations | 1,296 studies

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Normal tissues	Score
Fat body	100
Mucosa of mouth	93
Superior vena cava	91
Penis	86
Uterine tube	84
Putamen	83

View Top Normal tissues

Compounds	Score
Anisaldehyde	100
Allicin	99
Ecdysterone	95
Thymol	94
Dictamnine	92
Electric Fields	82

View Top Compounds

Diseases	Score
Dehydration	100
Papilloma of skin	96
Encephalomyelitis	95
Corneal burn	93
Pre B-cell acute lym…	88
Common acute lymphob…	88

View Top Diseases

Individual Studies
Soleus and gastrocnemius muscle from freely ambulatory or hind-limb suspended rats score: 100 | Mus musculus |   RNA Expression Gene expression changes induced by acute skeletal muscle unloading was investigated by hind-limb suspension (HLS) treatment of mice. Authors: Mazzatti J Dawn, Smith A Melissa, Oita C Radu et al. Organization: Unilever Colworth Science Park Sharnbroo…	Expression profile of HDAC treated LNCaP cells score: 71 | Homo sapiens |   RNA Expression Genome wide expression changes in LNCaP cells following treatment with the HDACs (Histone Deacetylase Inhibitor) CG-1521 (7.5uM) or TSA (Trichostatin A) Authors: Roy S, Jeffrey R, Tenniswood M Organization: University of Notre Dame Biological Scie…

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Literature | 10,108 results

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• Enhancing immunity through autophagy.

  Authors: Christian Münz

  Annual review of immunology 2009

• Autophagy genes in immunity.

  Authors: Herbert W Virgin, Beth Levine

  Nature immunology 2009 May

Associated Researchers

Thought leaders and organizations working on research involving autophagy.

View All Authors

• Noboru Mizushima
• Beth Levine
• Keiji Tanaka
• Tamotsu Yoshimori
• Masaaki Komatsu

View All Clinical Trials Sponsors

• Cancer Institute of New Jersey
• University of Pennsylvania
• University of Medicine and Dentistry New Jersey
• All India Institute of Medical Sciences, New Delhi
• Maastricht Radiation Oncology

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• Tokyo Medical and Dental University
• Osaka University
• Washington University School of Medicine
• University of Graz
• University of California

Clinical Trials | 13 trials

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• Hydroxychloroquine in Patients With Stage III or Stage IV Melanoma That Can Be Removed by Surgery

  conditions: Melanoma (Skin)

  interventions: hydroxychloroquine ; gene expression analysis ; laboratory biomarker analysis ; pharmacological study

   

• Ixabepilone and Hydroxychloroquine in Treating Patients With Metastatic Breast Cancer

  conditions: Breast Cancer

  interventions: hydroxychloroquine ; ixabepilone

   

News | 22 stories

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• HIV uses autophagy for its own means

  Biology News Net. - July 27, 2009

• ATM tumor-suppressor also recognizes damage caused by ROS and orders autophagy

  News-Medical. - February 19, 2010

Community

View All NextBio Users | 4 people

• Tong  Zhu

• takeshi  noda

View All NextBio Groups | 1 group

• Breast Cancer Integrated Knowledge Group

  26 members

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