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A supraventricular arrhythmia characterized by uncoordinated atrial myocardium activation due to multiple reentry circuits with consequent deterioration of atrial mechanical function. Instead of intermittently contracting, the atria quiver continuously in a chaotic pattern, causing a totally irregular, often tachycardia ventricular rate. On the ECG it is described by the replacement of consistent P waves by rapid oscillations or fibrillatory waves that vary in size, shape, and timing, associated with an irregular, frequently rapid ventricular response when atrioventricular conduction is intact.

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Data Correlations | 2 studies

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Genes category icon Genes
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GJA5 100 100
406216 100 100
KCNE2 100 100
KCNQ1 100 100
SPP1 97 97
BMP10 94 94
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Biogroups category icon Biogroups
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I49 - proSAAS 100 100
I47 - latexin 95 95
I8 - chymotrypsin/elastase inhibit… 93 93
Calcium Signaling by HBX of Hepatit… 93 93
Collagen helix repeat 93 93
Type III Secretion System 93 93
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Individual Studies

  • Atrial tissue of patients with atrial fibrillation and sinus rhythm

    Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    The purpose of our investigation was to identify the transcriptional basis for ultrastructural and functional specialization of human atria and ventricles.

    Authors: Barth AS, Merk S, Arnoldi E et al.

    Organization: University of Munich (LMU), Grosshadern …

  • OMIM - Fibrillation

    Homo sapiens Homo sapiens | Mutations/Phenotypic   Mutations/Phenotypic

    This study contains curated human phenotype data extracted from OMIM. Additional computational processing and curation of the phenotype data was performed to further organize and group data from related phenotypes into unifying disease categories.

    Source: NextBio Library/Mutation and Phenotypic data
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Associated Researchers

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Thought leaders and organizations working on research involving atrial fibrillation.

View All Author iconAuthors
  • Patrick T Ellinor
  • Emelia J Benjamin
  • Daniel Levy
  • Stanley Nattel
  • Ramachandran S Vasan
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • Deutsches Herzzentrum Muenchen
  • Procter and Gamble
  • Department of Veterans Affairs
  • Guidant Corporation
  • National Taiwan University Hospital
View All Affiliations icon Organizations
  • City Hospital
  • Massachusetts General Hospital
  • Montreal Heart Institute and Université de Montréal
  • Leiden University Medical Center
  • Blood Institute's Framingham Heart Study

Clinical Trials | 1,535 trials

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