A glial tumor of the brain or spinal cord showing astrocytic differentiation. It includes the following clinicopathological entities: pilocytic astrocytoma, diffuse astrocytoma, anaplastic astrocytoma, pleomorphic xanthoastrocytoma, subependymal giant cell astrocytoma, and glioblastoma.

Data Correlations | 13 studies

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Genes	Score
EGFR	100
PTEN	100
APC	100
NF1	100
TP53	100
KLF6	100

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Biogroups	Score
Focal Adhesion	100
P53 Signaling Pathway	100
Blockade of Neurotransmitter Relase…	99
Cell Cycle	99
ECM Receptor Interaction	99
Cardiac Protection Against Ros	99

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Individual Studies

Differential gene expression in astrocytic tumours Homo sapiens |   RNA Expression This study aims at investigating differential gene expression in human astrocytic tumours of grades I, II, III and IV. A total of 65 tumours were assessed using the Affymetrix U133A GeneChip. The study aims not only at discovering the main expression differences between astrocytic tumours of distinc… Authors: Petalidis L, Wayland M, Freeman T et al. Organization: University of Cambridge Cambridge CB2 2Q…

Pilocytic astrocytoma Homo sapiens |   RNA Expression Pilocytic astrocytomas (PAs) are the most common glioma in children. While many PAs Authors: Sharma MK, Mansur DB, Reifenberger G et al. Organization: Washington University School of Medicine…

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Literature | 112,729 results

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• CpG Island Hypermethylation in Human Astrocytomas.

  Authors: Xiwei Wu, Tibor A Rauch, Xueyan Zhong, William P Bennett, Farida Latif, Dietmar Krex, Gerd P Pfeifer

  Cancer research 2010 Mar 16

• Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model.

  Authors: Sheila Alcantara Llaguno, Jian Chen, Chang-Hyuk Kwon, Erica L Jackson, Yanjiao Li, Dennis K Burns, Arturo Alvarez-Buylla, Luis F Parada

  Cancer cell 2009 Jan 6

Associated Researchers

Thought leaders and organizations working on research involving astrocytoma.

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• Eva Y-H P Lee
• Jian Chen
• Rubén Martín
• Chang-Hyuk Kwon
• Joanna J Moser

View All Clinical Trials Sponsors

• Schering-Plough
• Burzynski Research Institute
• Neopharm
• Antisense Pharma
• University of Pittsburgh

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• University of Calgary
• Washington University School of Medicine
• University of North Carolina at Chapel Hill
• University of Texas Southwestern Medical Center at Dallas
• University of Utah

Clinical Trials | 366 trials

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• SCH 52365 Phase II Clinical Study: A Study on the Efficacy and Safety of Monotherapy With SCH 52365 in Patients With First Relapsed Anaplastic Astrocytoma (Study P03745)(COMPLETED)

  conditions: Astrocytoma

  interventions: Temozolomide

   

• Radiotherapy for Malignant Astrocytomas in the Elderly

  conditions: Primary Brain Tumor ; Anaplastic Astrocytoma ; Glioblastoma Multiforme

  interventions: Radiotherapy

   

News | 8 stories

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• Heidelberg neuropathologists detect astrocytomas that can deactivate the "death receptor"

  News-Medical.net. - September 01, 2009

• Antisense Pharma's SAPPHIRE Phase III trial evaluating trabedersen approved by Health Canada

  News-Medical. - October 19, 2009

Community

View All NextBio Users | 3 people

• Nahin  Hussain

• Manoj  Mishra

  Postdotoral Fellow

  University of Calgary

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