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An infectious fungal disease that occurs most often in the skin, ears, nasal sinuses, and lungs of people with suppressed immune systems.

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Data Correlations | 3 studies

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Genes category icon Genes
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CXCL2 100 100
FSTL1 94 94
CXCL1 90 90
PPAP2B 90 90
EGR1 87 87
CCL3 86 86
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Biogroups category icon Biogroups
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IL-1R Pathway 100 100
DNA Replication Reactome 100 100
Erythrocyte Differentiation Pathway 99 99
Small chemokine, interleukin-8-like 98 98
Cytokine Cytokine Receptor Interact… 98 98
Tumor Necrosis Factor Pathway 98 98
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Individual Studies

  • Human dendritic cells after infection with A. fumigatus

    Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    DCs are localized under the mucosa of the lungs and the gastrointestinal tract, and therefore come into close contact with A. fumigatus germ tubes during early steps of infection as soon as fungi become invasive. For a more detailed insight into differentially regulated genes, whole genome microarra…

    Authors: Mezger Markus, Kneitz Susanne, Löffler Jürgen

    Organization: Universitätsklinikum Würzburg Medizinisc…

  • C57Bl/6 or gp91phox-/- AM after exposure to conidia or polystyrene beads

    Mus musculus Mus musculus | RNA Expression   RNA Expression

    The response of AM transcription to exposure to conidia is expected to provide information about the mechanism by which these cells prevent conidial germination and therefore invasive aspergillosis.

    Authors: Burritt James, Cornish Jean, Hurtgen Brady et al.

    Organization: Montana State University Microbiology Fu…
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Associated Researchers

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Thought leaders and organizations working on research involving aspergillosis.

View All Author iconAuthors
  • Thomas J Walsh
  • Diana Mickiene
  • Masafumi Seki
  • Willem J G Melchers
  • Hiroshi Kakeya
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • Pfizer
  • Astellas Pharma Inc
  • National Cancer Institute (NCI)
  • Merck
  • University of Pittsburgh
View All Affiliations icon Organizations
  • National Institutes of Health
  • Nagasaki University Graduate School of Biomedical Sciences
  • National Cancer Institute
  • University of Texas Health Science Center at San Antonio
  • University of Bern

Community

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