thickening and loss of elasticity of arterial walls; atherosclerosis is the most common form of arteriosclerosis and involves lipid deposition and thickening of the intimal cell layers within arteries; additional forms of arteriosclerosis involve calcification of the media of muscular arteries (Monkeberg medial calcific sclerosis) and thickening of the walls of small arteries or arterioles due to cell proliferation or hyaline deposition (arteriolosclerosis).

Data Correlations | 10 studies

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Genes	Score
MMP3	100
CD36	100
387573	100
338334	100
387584	100
387585	100

View Top Genes

Biogroups	Score
Small chemokine, interleukin-8-like	100
Cytokine Cytokine Receptor Interact…	97
EGF-like region, conserved site	97
Immunoglobulin subtype	97
Natural Killer Cell Mediated Cytoto…	96
Toll-like Receptor Signaling Pathwa…	95

View Top Biogroups

Individual Studies

Myocardial remodeling in response to left ventricular assist device (LVAD) implant Homo sapiens |   RNA Expression 19 paired human left ventricular apex samples were harvested at the time of implant of a left ventricular assist device (PRE) and at the time of explant (POST). The cohort included patients that were clinically classified as "ischemic" (I) showing evidence of coronary artery disease, "non-ischemic" … Authors: Hall J, Grindle SM, Han X et al. Organization: Lillehei Heart Institute Division of Car…

Simvastatin treatment of HPBM-macrophages Homo sapiens |   RNA Expression HMG-CoA reductase inhibitors, statins, have beneficial vascular effects beyond their cholesterol-lowering action. These pleiotropic effects include an anti-inflammatory effect on macrophages. Since macrophages play a central role in atherogenesis, we further characterized the effects on peripheral b… Authors: Tuomisto T Tiina, Lumivuori Henri, Kansanen Emilia et al. Organization: A.I.Virtanen Institute Molecular Medicin…

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Literature | 79,939 results

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• Stem cells and transplant arteriosclerosis.

  Authors: Qingbo Xu

  Circulation research 2008 May 9

• Impact of kidney disease and blood pressure on the development of cardiovascular disease: an overview from the Japan Arteriosclerosis Longitudinal Study.

  Authors: Toshiharu Ninomiya, Yutaka Kiyohara, Yosuke Tokuda, Yasufumi Doi, Hisatomi Arima, Akiko Harada, Yasuo Ohashi, Hirotsugu Ueshima, Japan Arteriosclerosis Longitudinal Study Group

  Circulation 2008 Dec 16

Associated Researchers

Thought leaders and organizations working on research involving arteriosclerosis.

View All Authors

• Akiko Harada
• Kathryn J Wood
• Stephan M Ensminger
• Qingbo Xu
• Yasuo Ohashi

View All Clinical Trials Sponsors

• National Heart, Lung, and Blood Institute (NHLBI)
• Boehringer Ingelheim Pharmaceuticals
• National Taiwan University Hospital
• Pfizer
• Kantonsspital Bruderholz

View All Organizations

• Yale University School of Medicine
• Brigham and Women's Hospital
• University of Helsinki and Helsinki University Central Hospital
• King's College London
• Kyushu University

Clinical Trials | 233 trials

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• Early Detection of Arteriosclerosis

  conditions: Arteriosclerosis ; Atherosclerosis ; Myocardial Infarction ; Stroke ; Diabetes Mellitus ; Peripheral Arterial Occlusive Disease

  interventions: none

   

• Coronary Arteriosclerosis in Patients With Acute Ischemic Stroke

  conditions: Ischemic Stroke ; Myocardial Ischemia ; Coronary Arteriosclerosis

  interventions: none

   

News | 8 stories

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• Anti-PC antibody linked to reduced risk of arteriosclerosis

  News-Medical. - February 12, 2010

• VIA Pharmaceuticals to Present Poster at AHA Arteriosclerosis, Thrombosis and Vascular Biology Conference 2009

  PR Newswire. - March 31, 2009

Community

View All NextBio Users | 1 person

• Gino  Fornaciari

  Prof.

  University of Pisa

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