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Inflammatory joint disease affecting the spine. It occurs predominantly in young males and produces pain and stiffness as a result of inflammation of the sacroiliac, intervertebral, and costovertebral joints. Etiology is unknown.

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Data Correlations | 2 studies

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Genes category icon Genes
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HLA-A 100 100
ITM2A 100 100
GBP5 94 94
CTLA4 92 92
INDO 90 90
RSAD2 89 89
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Biogroups category icon Biogroups
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CTL Mediated Immune Response Agains… 100 100
Natural Killer Cell Mediated Cytoto… 99 99
Cell Adhesion Molecules (CAMs) 98 98
Antigen Processing and Presentation 96 96
MHC classes I and II-like antigen r… 94 94
Immunoglobulin C1-set 94 94
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Individual Studies

  • OMIM - Arthropathies

    Homo sapiens Homo sapiens | Mutations/Phenotypic   Mutations/Phenotypic

    This study contains curated human phenotype data extracted from OMIM. Additional computational processing and curation of the phenotype data was performed to further organize and group data from related phenotypes into unifying disease categories.

    Source: NextBio Library/Mutation and Phenotypic data

  • Expression of macrophages from ankylosing spondylitis patients treated with IFN-gamma

    Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    Macrophages were derived from the peripheral blood of 8 ankylosing spondylitis patients and 9 healthy control subjects over 7 days with the use of granulocyte-macrophage colony-stimulating factor. Cells were stimulated for 24 hours with interferon or were left untreated for 24 hours.

    Authors: Smith H Judy, Barnes G Michael, Hong Dihua et al.

    Organization: Cincinnati Childrens Hospital Medical Ce…
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Associated Researchers

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Thought leaders and organizations working on research involving ankylosing spondylitis.

View All Author iconAuthors
  • Matthew A Brown
  • Michael M Ward
  • John D Reveille
  • Walter P Maksymowych
  • John C Davis
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • Wyeth
  • Charite University, Berlin, Germany
  • National Institute of Arthritis and Musculoskeletal and Skin Diseases …
  • Abbott
  • Schering-Plough
View All Affiliations icon Organizations
  • National Institute of Arthritis and Musculoskeletal and Skin Diseases
  • University of Queensland
  • University of Alberta
  • Leiden University Medical Center
  • Charité--Universitätsmedizin Berlin

Clinical Trials | 216 trials

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