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Description: A stable adenosine A1 and A2 receptor agonist. Experimentally, it inhibits cAMP and cGMP phosphodiesterase activity. [PubChem]
Drug Type: Small Molecule; Experimental
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Data Correlations | 1 study

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Genes category icon Genes
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IL6 100 100
CTGF 99 99
NR4A1 99 99
FOS 93 93
DDIT4 91 91
RGS2 89 89
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Biogroups category icon Biogroups
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Regulation of Spermatogenesis by CR… 100 100
Regulation of hematopoiesis by cyto… 100 100
Four-helical cytokine, core 99 99
Four-helical cytokine-like, core 99 99
Cytokine Network 99 99
Basic-leucine zipper (bZIP) transcr… 99 99
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Individual Studies

  • Murine pituitary folliculostellate TtT/GF cells treated with 5'-N-ethylcarboxamidoadenosine

    Mus musculus Mus musculus | RNA Expression   RNA Expression

    Folliculostellate cells within the anterior pituitary gland do not secrete any of the classical hormones but do express cytokines and growth factors. Cultures of TtT/GF cells were treated with 10uM NECA (5'-N-ethylcarboxamidoadenosine) for 30 and 120 minutes.

    Authors: Ham Jack

    Organization: Cardiff University Centre for Endocrine …
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Associated Researchers

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Thought leaders and organizations working on research involving Zinc03995399.

View All Author iconAuthors
  • Igor Feoktistov
  • Dewan Zeng
  • James M Downey
  • Michael V Cohen
  • Italo Biaggioni
View All Affiliations icon Organizations
  • University of South Alabama
  • University of North Carolina at Chapel Hill
  • University of Medicine and Dentistry of New Jersey
  • Gorlaeus Laboratories
  • Università di Pisa

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