Zinc finger (Znf) domains are relatively small protein motifs that bind one or more zinc atoms, and which usually contain multiple finger-like protrusions that make tandem contacts with their target molecule. They were first identified as a DNA-binding motif in transcription factor TFIIIA from Xenopus laevis, however they are now recognised to bind DNA, RNA, protein and/or lipid substrates. Their binding properties depend on the amino acid sequence of the finger domains and of the linker between fingers, as well as on the higher-order structures and the number of fingers. Znf domains are often found in clusters, where fingers can have different binding specificities. There are many superf...

Data Correlations | 529 studies

View All

Normal tissues	Score
Interstitial cell of…	100
Trigeminal ganglion	78
Spinal cord	67
Set of seminiferous …	66
Testis	48
Haploid nucleated ce…	40

View Top Normal tissues

Compounds	Score
Gelatine	100
Bovinocidin	96
Actinomycin D	95
Puy	85
Quintozene	85
Bismuth, Isotope Of …	83

View Top Compounds

Diseases	Score
Malignant teratoma o…	100
Yolk sac tumor	98
Choriocarcinoma	93
Conn syndrome	84
Helicobacter-associa…	82
Seminoma of testis	82

View Top Diseases

Individual Studies
Developmental time course of whole ovary at gd 11, 12, 14, 16, 18 and pnd2. score: 100 | Mus musculus |   RNA Expression The overall objective of this proposal is to map the temporal and spatial dynamics of gene expression in the fetal mouse testis at key developmental timepoints Authors: Gaido K, Lehmann K Organization: MRC Human Genetics Unit GUDMAP Database …	Leukocyte Gene Expression after Burn Injury or Trauma Hemorrhage in Mice score: 93 | Mus musculus |   RNA Expression Genes that are sequentially expressed in white blood cells from blood and spleen at 2 hours, 2 day,3 days, and 7 days after burn injury or trauma-hemorrhage. Authors: Lederer JA, Brownstein BH, Lopez MC et al. Organization: Massachusetts General Hospital Departmen…

View All Individual Studies

Literature | 5 results

View All

• A novel mammalian flavin-dependent histone demethylase.

  Authors: Aristotele Karytinos, Federico Forneris, Antonella Profumo, Giuseppe Ciossani, Elena Battaglioli, Claudia Binda, Andrea Mattevi

  The Journal of biological chemistry 2009 Jun 26

• Dynamic RNA profiling in Plasmodium falciparum synchronized blood stages exposed to lethal doses of artesunate.

  Authors: Onguma Natalang, Emmanuel Bischoff, Guillaume Deplaine, Caroline Proux, Marie-Agnès Dillies, Odile Sismeiro, Ghislaine Guigon, Serge Bonnefoy, Jintana Patarapotikul, Odile Mercereau-Puijalon,…

  BMC genomics 2008

Associated Researchers

Thought leaders and organizations working on research involving Zinc finger, CW-type.

View All Authors

• Nikola A Bowden
• Antonella Profumo
• Rodney J Scott
• Elena Battaglioli
• John MacKay

View All Organizations

• University of Newcastle
• Institut Pasteur
• Université Laval
• Università di Pavia
• Pennsylvania State University

Community

NextBio Users

• No NextBio users were found for “Zinc finger, CW-type”.
  Complete your user profile with your interests, if you want others to find you within the NextBio community.

NextBio Groups

• No NextBio groups were found for “Zinc finger, CW-type”.
  Be the first to start a group and share your interests with others within the NextBio community.

search → result

search → result