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Description: A purine base found in most body tissues and fluids, certain plants, and some urinary calculi. It is an intermediate in the degradation of adenosine monophosphate to uric acid, being formed by oxidation of hypoxanthine. The methylated xanthine compounds caffeine, theobromine, and theophylline and their derivatives are used in medicine for their bronchodilator effects. (Dorland, 28th ed)
Drug Type: Small Molecule; Experimental
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Data Correlations | 6 studies

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Individual Studies

  • Drug target sets for approved compounds

    Homo sapiens Homo sapiens | Therapeutic   Therapeutic

    The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information.

    Authors: David S Wishart, Craig Knox, An Chi Guo et al.

    Organization: Department of Computing Science, Univers…
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Associated Researchers

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Thought leaders and organizations working on research involving Xanthine.

View All Author iconAuthors
  • Meng Li
  • Xiaofen Li
  • Robert P Hausinger
  • Palraj Kalimuthu
  • S Abraham John
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • Alexza Pharmaceuticals, Inc.
  • Sanofi-Aventis
  • Actavis Inc.
  • Ranbaxy Laboratories Limited
  • Alkermes
View All Affiliations icon Organizations
  • National University of Singapore
  • Université Paris-Sud
  • CV Therapeutics Inc
  • Michigan State University
  • Gandhigram Rural University

Clinical Trials | 296 trials

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News | 1 story

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