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Description: A unicyclic, aminoketone antidepressant. The mechanism of its therapeutic actions is not well understood, but it does appear to block dopamine uptake. The hydrochloride is available as an aid to smoking cessation treatment.
Molecular weight: 239.741 g/mol
Molecular formula: C13H18ClNO
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Data Correlations | 4 studies

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Genes category icon Genes
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SLC6A3 100 100
SLC6A2 100 100
Mbl1 100 100
GZMB 99 99
RGD1561637_predicted 97 97
STAC3 97 97
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Biogroups category icon Biogroups
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Multi-Drug Resistance Factors (MRP … 100 100
1,2-Dichloroethane Degradation 99 99
Cytochrome P450 Protein Family 98 98
PPAR Signaling Pathway 98 98
ALK Pathway 98 98
Metabolism of Xenobiotics by Cytoch… 98 98
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Individual Studies

  • Broad Connectivity Map (CMAP 2.0) compound database

    Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    A reference collection of genome-wide transcriptional expression data from cultured human cells treated with bioactive small molecules that enable the discovery of functional connections between drugs, genes and diseases through the transitory feature of common gene-expression changes.

    Authors: Lamb J

    Organization: Broad Institute Seven Cambridge Center C…

  • Drug target sets for approved compounds

    Homo sapiens Homo sapiens | Therapeutic   Therapeutic

    The DrugBank database is a unique bioinformatics and cheminformatics resource that combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information.

    Authors: David S Wishart, Craig Knox, An Chi Guo et al.

    Organization: Department of Computing Science, Univers…
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Associated Researchers

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Thought leaders and organizations working on research involving Wellbutrin.

View All Author iconAuthors
  • Bruce E Blough
  • Monique P Curran
  • Maurizio Fava
  • Lily P H Yang
  • Hugo R Arias
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • National Institute on Drug Abuse (NIDA)
  • Actavis Inc.
  • GlaxoSmithKline
  • Sandoz Inc.
  • University of California, San Francisco
View All Affiliations icon Organizations
  • Massachusetts General Hospital
  • Research Triangle Institute
  • University of Toronto
  • Johns Hopkins University School of Medicine
  • California Institute of Technology

Clinical Trials | 334 trials

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News | 13 stories

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