Uracil(Uridine) - NextBio

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Search Term: Uracil (treatment: Uridine)

Overview

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PubChem Substance 3593

Drug Type:

Small Molecule; Experimental

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Data Correlations | 21 studies

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Individual Studies

Drug-Induced Renal Tubular Toxicity

Rattus norvegicus | RNA Expression

These data support the publication titled "A Gene Expression Signature that Predicts the Future Onset of Drug-Induced Renal Tubular Toxicity"

Authors: Fielden MR, Eynon BP, Natsoulis G et al.

Organization: Iconix Pharmaceuticals 325 E Middlefield…

Rhabdomyosarcoma A673 cell treatments: Cytarabine, Doxorubicin and Puromycin

Homo sapiens | RNA Expression

An increasing number of cancer-associated mutations have been identified. Unfortunately, little therapy today exploits these tumor-specific genetic lesions. Often, the resulting oncoproteins have been intractable to easy manipulation with current small molecule screening approaches. To overcome this…

Authors: Stegmaier K, Wong JS, Ross KN et al.

Organization: Dana-Farber Cancer Institute and Childre…

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Literature | 19,582 results

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Enzymatic capture of an extrahelical thymine in the search for uracil in DNA.

Authors: Jared B Parker, Mario A Bianchet, Daniel J Krosky, Joshua I Friedman, L Mario Amzel, James T Stivers
Nature 2007 Sep 27
Keeping uracil out of DNA: physiological role, structure and catalytic mechanism of dUTPases.

Authors: Béata G Vértessy, Judit Tóth
Accounts of chemical research 2009 Jan 20

Associated Researchers

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Thought leaders and organizations working on research involving Uracil.

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Bernard A Connolly
Bodil Kavli
Geir Slupphaug
Hans E Krokan
Elena A Kouzminova

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Clinical Trials Sponsors

Taiho Pharma USA, Inc.
Taiho Pharmaceutical Co., Ltd.
Quintiles
National Taiwan University Hospital
Tokyo University

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Affiliations icon

University of Illinois at Urbana-Champaign
Johns Hopkins Medical School
Institute of Enzymology
Whitehead Institute for Biomedical Research
Institut de Recherches Cliniques de Montréal

Clinical Trials | 43 trials

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Sorafenib Plus Tegafur/Uracil (UFUR®) for Hepatocellular Carcinoma (HCC)

conditions: Hepatocellular Carcinoma

interventions: Sorafenib ; tegafur/uracil (UFUR®)
Metronomic Chemotherapy With Tegafur/Uracil for Head and Neck Squamous Cell Carcinoma

conditions: Head and Neck Cancer

interventions: tegafur-uracil

News | 75 stories

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U.S. regulators pressed to speed up BPA decision
Reuters. - January 15, 2010
Pakistan Taliban chief said targeted by U.S. drone
Reuters. - January 14, 2010

Community

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NextBio Users | 4 people

Peter M. Wilson
Senior Post-doctoral Research Fellow

University of Southern California

Donald Anderson
Research Support Specialist

Cornell University

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