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neuropsychological disorder related to alterations in dopamine metabolism and neurotransmission involving frontal-subcortical neuronal circuits; both multiple motor and one or more vocal tics need to be present with tics occurring many times a day, nearly daily, over a period of more than one year; disturbance causes marked distress or significant impairment in social, occupational, or other important areas of functioning.
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Authors: Elizabeth R Sowell, Eric Kan, June Yoshii, Paul M Thompson, Ravi Bansal, Dongrong Xu, Arthur W Toga, Bradley S Peterson
Nature neuroscience 2008 JunAuthors: Roger L Albin, Jonathan W Mink
Trends in neurosciences 2006 MarThought leaders and organizations working on research involving Tourette's syndrome.
conditions: Gilles de la Tourette Syndrome
interventions: Deep brain stimulation
conditions: Gilles de la Tourette's Syndrome
interventions: Facial expression recognition of emotion
Director, Scientific and Medical Affairs
Teva Neuroscience, Inc
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