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tuberous sclerosis 1

This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

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Data Correlations | 1,265 studies

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Tissues category icon Normal tissues
Score Help
Superior vena cava 100 100
Pericardium 88 88
Vestibular nuclear c… 77 77
Nipple 74 74
Ciliary ganglion 72 72
Mucosa of pharynx 70 70
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Compounds category icon Compounds
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Strontium 100 100
Pergolide 90 90
Flexamine G 83 83
Ferulic Acid 80 80
Benzamil 80 80
Propranolol 78 78
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Diseases category icon Diseases
Score Help
Tuberous sclerosis 100 100
Cortical dysplasia 100 100
Pulmonary lymphangio… 100 100
Renal cell carcinoma 98 98
Hamartoma 98 98
Streptococcal pneumo… 55 55
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Individual Studies

  • Mouse Phenotypes - Neurocutaneous syndrome

    score: 100100 | Mus musculus Mus musculus | Mutations/Phenotypic   Mutations/Phenotypic

    This study contains curated mouse gene mutation data extracted from the Mouse Genome Database (MGD) at The Jackson Laboratory, Bar Harbor, Maine. Additional computational processing and curation of mouse phenotype data was performed to further organize and group data from related phenotypes into uni…

    Source: NextBio Library/Mutation and Phenotypic data

  • Cancer census - gene mutations in cancer and other diseases

    score: 100100 | Homo sapiens Homo sapiens | Mutations/Phenotypic   Mutations/Phenotypic

    The Cancer Gene Census is an ongoing effort to catalogue those genes for which mutations have been causally implicated in cancer. The original census and analysis was published in Nature Reviews Cancer

    Authors: P Andrew Futreal, Lachlan Coin, Mhairi Marshall et al.

    Organization: Cancer Genome Project, Human Genome Anal…
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Associated Researchers

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Thought leaders and organizations working on research involving TSC1.

View All Author iconAuthors
  • David J Kwiatkowski
  • Jeremy P Cheadle
  • Leif W Ellisen
  • Elizabeth P Henske
  • James Brugarolas
View All Clinical trial sponsors icon Clinical Trials Sponsors
  • National Taiwan University Hospital
  • M.D. Anderson Cancer Center
  • National Cancer Institute (NCI)
  • University of Utah
  • Vanderbilt-Ingram Cancer Center
View All Affiliations icon Organizations
  • University of California
  • Brigham and Women's Hospital
  • Harvard Medical School
  • University of California, San Francisco
  • Dana-Farber Cancer Institute

Clinical Trials | 58 trials

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News | 3 stories

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Community

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