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ST3 beta-galactoside alpha-2,3-sialyltransferase 4

Synthesis of alpha-2,3-linked sialic acid to Gal(beta-1,3)GalNAc is mediated by at least 3 distinct beta-galactoside alpha-2,3-sialyltransferases (EC 2.4.99.4), including ST3GAL4. In contrast, only a single gene encodes the beta-galactoside alpha-2,6-sialyltransferase (EC 2.4.99.1), ST6GAL1 (MIM 109675) (Chang et al., 1995 [PubMed 7655169]).[supplied by OMIM]

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Data Correlations | 1,242 studies

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Tissues category icon Normal tissues
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Cecum 100 100
Duodenum 86 86
Adrenal gland 85 85
Adrenal cortex 79 79
Set of fingers 79 79
Thyroid gland 78 78
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Compounds category icon Compounds
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Hecogenin 100 100
U 62066 91 91
Bacteroides Fragilis… 90 90
Paromomycin 81 81
Pronethalol 70 70
Hymecromone 68 68
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Diseases category icon Diseases
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Infectious colitis 100 100
Postpartum cardiomyo… 83 83
Scarlet fever 75 75
Helicobacter-associa… 72 72
Granular cell tumor 70 70
Intestinal metaplasi… 69 69
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Individual Studies

  • Mouse Model of Infectious Colitis

    score: 100100 | Mus musculus Mus musculus | RNA Expression   RNA Expression

    Examination of host genome-wide changes upon encounters with pathogens provides insight into the pathogenesis of infection and disease. When performed comparatively, it may shed light on the mechanisms underlying host susceptibility. In this study, gene expression in the mouse colon was investigated…

    Authors: Borenshtein Diana, Fry C Rebecca, Groff B Elizabeth et al.

    Organization: MIT Cambridge MA 02139 Country USA

  • Broad Connectivity Map (CMAP 2.0) compound database

    score: 9999 | Homo sapiens Homo sapiens | RNA Expression   RNA Expression

    A reference collection of genome-wide transcriptional expression data from cultured human cells treated with bioactive small molecules that enable the discovery of functional connections between drugs, genes and diseases through the transitory feature of common gene-expression changes.

    Authors: Lamb J

    Organization: Broad Institute Seven Cambridge Center C…
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Associated Researchers

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Thought leaders and organizations working on research involving ST3GAL4.

View All Author iconAuthors
  • Christopher A Wienczewski
  • Svetlana V Kashirina
  • António J Moreno
  • Grietje Molema
  • Nelya N Samovilova
View All Affiliations icon Organizations
  • University of Copenhagen
  • Institute of Molecular and Cellular Medicine
  • University of Pittsburgh
  • Heidelberg University
  • ARC-Onderstepoort Veterinary Institute

Community

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