Breast cancer cell lines treated with doxorubicin and p53-RNAi

score: 100 | Homo sapiens |   RNA Expression

p53-dependent gene expression signatures of four cell lines (MCF-7, ZR-75-1, and two immortalized human mammary epithelial cell lines) were identified by comparing p53-RNAi transduced cell lines to their parent cell lines.

Organization: University of North Carolina at Chapel H…

Gene activation by Rag-mediated DNA double strand breaks

score: 100 | Mus musculus |   RNA Expression

The objective is to identify genes that are differentially expressed following the introduction of DNA double strand breaks (DSBs) by the Rag proteins in murine pre-B cells. Cells lacking Artemis are used since the Rag-induced DSBs will not be repaired and, thus, will provide a continuous stimulus t…

Authors: Bredemeyer AL, Helmink BA, Innes CL et al.

Organization: NIEHS DIR Microarray Core 111 T.W. Alexa…