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ribosomal protein S12
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S12E family of ribosomal proteins. It is located in the cytoplasm. Increased expression of this gene in colorectal cancers compared to matched normal colonic mucosa has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq]
Normal tissues
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|
||
|---|---|---|---|
| Thyroid gland |
100
|
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| Thymus |
94
|
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| Adrenal gland |
93
|
||
| Caudate nucleus |
91
|
||
| Uterus |
85
|
||
| Segment of tracheobr… |
83
|
Compounds
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|
||
|---|---|---|---|
| Zinc01576887 |
100
|
||
| Fusidic Acid |
83
|
||
| Gingerol |
82
|
||
| 4-14-00-01130 (beils… |
69
|
||
| Lobeline [inn] |
66
|
||
| Cefalexin |
63
|
 Individual Studies |
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|---|---|
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Saccharomyces cerevisiae
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RNA Expression
Homo sapiens
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Characterization of the promoter of the Brugia malayi 12kDa small subunit ribosomal protein (RPS12) gene.
Authors: Ana de Oliveira, Charles R Katholi, Thomas R Unnasch
International journal for parasitology 2008 Aug -
Antibacterial discovery in actinomycetes strains with mutations in RNA polymerase or ribosomal protein S12.
Authors: Takeshi Hosaka, Mayumi Ohnishi-Kameyama, Hideyuki Muramatsu, Kana Murakami, Yasuhisa Tsurumi, Shinya Kodani, Mitsuru Yoshida, Akihiko Fujie, Kozo Ochi
Nature biotechnology 2009 May
Thought leaders and organizations working on research involving RPS12.
- National Food Research Institute
- University of California
- Johns Hopkins University School of Medicine
- Yakult Central Institute for Microbiological Research
- Brown University
